Nutrition support practices in critically ill head-injured patients: a global perspective

Table 4 Relationship between energy and protein deficit and length of mechanical ventilation and time to discharge alive

Variable		Time until discharged alive from ICU (days)		Time until discharged alive from hospital (days)		Length of mechanical ventilation (days)
Variable		Hazard ratio (95 % CI)	p	Hazard ratio (95 % CI)	p	Hazard ratio (95 % CI)	P
All patients		n = 1027 energy, 1026 protein		n = 1027 energy, 1026 protein		n = 896
	Energy deficit (kcal/day)	1.04 (1.02, 1.05)	<0.001	1.03 (1.01, 1.04)	0.002	1.07 (1.05, 1.08)	<0.001
	OR is per 100 kcal/day	1.04 (1.02, 1.05)	<0.001	1.03 (1.01, 1.04)	0.002	1.07 (1.05, 1.08)	<0.001
	Protein deficit (g/day)	1.02 (1.01, 1.04)	0.001	1.02 (1.002, 1.03)	0.024	1.05 (1.03, 1.06)	<0.001
	OR is per 5 g/day	1.02 (1.01, 1.04)	0.001	1.02 (1.002, 1.03)	0.024	1.05 (1.03, 1.06)	<0.001
Patients who stayed at least 8 days		n = 816		n = 816		n = 732
	Energy deficit (kcal/day)	1.01 (0.99, 1.02)	0.948	1.02 (1.01, 1.04)	0.001	1.02 (1.01, 1.04)	0.004
	OR is per 100 kcal/day	1.01 (0.99, 1.02)	0.948	1.02 (1.01, 1.04)	0.001	1.02 (1.01, 1.04)	0.004
	Protein deficit (g/day)	0.99 (0.98, 1.01)	0.275	1.01 (0.99, 1.03)	0.316	1.01 (0.996, 1.03)	0.161
	OR is per 5 g/day	0.99 (0.98, 1.01)	0.275	1.01 (0.99, 1.03)	0.316	1.01 (0.996, 1.03)	0.161

Adjusted for age, sex, region, Acute Physiology and Chronic Health Evaluation II score, body mass index category, admission category, and clustering of patients within ICUs. OR odds ratio

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