Table 4 Subgroup analysis of 5-year cumulative mortality following first-time admission with myocardial infarction and cardiogenic shock comparing patients with and without AKI-RRT
Exposure | No. of deaths | No. of hospital survivorsa | No AKI-RRT 5-year risk % (95 % CI) | AKI-RTT 5-year risk % (95 % CI) | Hazard ratiob (95 % CI) |
|---|---|---|---|---|---|
Sex | |||||
Male | 479 | 2164 | 26.3 (24.0–28.9) | 44.7 (36.1–54.3) | 1.85 (1.41–2.43) |
Female | 264 | 895 | 34.9 (31.0–39.1) | 45.3 (30.2–63.7) | 1.04 (0.64–1.68) |
Age group (years) | |||||
<60 | 80 | 766 | 12.1 (9.3–15.5) | 32.4 (20.0–49.8) | 3.00 (1.67–5.40) |
60–69 | 185 | 966 | 23.0 (19.8–26.6) | 30.1 (20.5–44.7) | 1.24 (0.76–2.02) |
70–79 | 309 | 989 | 37.1 (33.2–41.3) | 60.6 (45.5–76.1) | 1.47 (0.82–2.57) |
≥ 80 | 169 | 338 | 58.7 (51.7–65.7) | 77.6 (51.9–95.3) | 1.45 (0.82–2.57) |
Comorbidities | |||||
Congestive heart failure | |||||
No | 658 | 2893 | 27.0 (24.9–29.2) | 43.2 (35.2–52.1) | 1.64 (1.28–2.11) |
Yes | 85 | 166 | 62.9 (52.9–73.0) | 62.3 (36.6–87.6) | 0.67 (0.33–1.25) |
Peripheral vascular disease | |||||
No | 613 | 2760 | 26.4 (24.3–28.7) | 43.5 (25.2–52.7) | 1.69 (1.31–2.19) |
Yes | 130 | 299 | 52.5 (44.9–60.4) | 55.8 (36.2–77.3) | 1.11 (0.33–1.35) |
Cerebrovascular disease | |||||
No | 631 | 2752 | 26.8 (24.7–29.1) | 42.8 (34.8–51.7) | 1.54 (1.20–1.98) |
Yes | 112 | 307 | 50.0 (42.0–58.7) | 60.9 (39.6–82.6) | 2.23 (1.16–4.28) |
Chronic pulmonary disease | |||||
No | 632 | 2802 | 26.6 (24.5–28.8) | 46.1 (37.9–55.1) | 1.86 (1.45–2.28) |
Yes | 111 | 257 | 52.7 (45.1–60.7) | 33.4 (17.3–58.1) | 0.56 (0.26–1.21) |
Hypertension | |||||
No | 668 | 2874 | 27.8 (25.7–30.0) | 42.5 (34.6–51.4) | 1.76 (1.33–2.32) |
Yes | 75 | 185 | 47.8 (38.2–58.3) | 68.4 (43.5–90.3) | 1.18 (0.77–1.80) |
Atrial fibrillation | |||||
No | 629 | 2938 | 28.1 (26.1–30.4) | 44.4 (36.7–52.9) | 1.56 (1.21–2.01) |
Yes | 74 | 195 | 50.1 (40.7–60.3) | 70.0 (45.5–90.7) | 1.53 (0.79–2.98) |
VTE | |||||
No | 726 | 3023 | 28.7 (26.6–30.8) | 45.2 (37.3–53.8) | 1.60 (1.26–2.03) |
Yes | 17 | 36 | 46.8 (30.1–67.2) | 40.0 (11.8–87.4) | 1.22 (0.27–5.46) |
Chronic kidney disease | |||||
No | 694 | 2964 | 28.0 (25.9–30.2) | 41.9 (34.0–50.8) | 1.60 (1.24–2.06) |
Yes | 49 | 95 | 67.9 (53.7–81.3) | 75.5 (48.5–95.0) | 0.94 (0.49–1.79) |
Liver disease | |||||
No | 729 | 3038 | 28.6 (26.5–30.8) | 44.6 (36.9–53.2) | 1.60 (1.26–2.03) |
Yes | 14 | 21 | 70.2 (45.3–91.2) | – | 0.73 (0.08–6.48) |
Diabetes mellitus | |||||
No | 590 | 2562 | 26.8 (24.6–29.1) | 42.2 (33.9–51.5) | 1.71 (1.31–2.24) |
Yes | 153 | 497 | 41.6 (35.6–48.3) | 58.0 (38.7–78.5) | 1.22 (0.75–1.99) |
Cancer | |||||
No | 661 | 2845 | 27.5 (25.4–29.7) | 44.7 (36.8–53.5) | 1.62 (1.27–2.07) |
Yes | 82 | 214 | 47.2 (38.8–56.5) | 49.2 (23.4–82.2) | 1.03 (0.41–2.58) |
Obesity | |||||
No | 724 | 2978 | 28.8 (26.7–31.0) | 44.7 (36.9–53.3) | 1.60 (1.26–2.03) |
Yes | 19 | 81 | 31.7 (19.9–48.0) | 60.2 (17.9–98.7) | 1.19 (0.33–4.28) |
In-hospital procedures | |||||
No CAG, PCI or CABG | 264 | 481 | 63.1 (57.5–68.6) | 51.3 (36.7–67.8) | 0.71 (1.26–2.03) |
PCI | 220 | 1185 | 22.7 (19.7–26.2) | 46.8 (35.7–60.8) | 2.26 (1.57–3.25) |
CABG | 217 | 1334 | 17.5 (15.0–20.2) | 37.7 (25.8–52.7) | 2.18 (1.38–3.44) |
MI subgroups | |||||
STEMI | 252 | 1199 | 25.8 (22.6–29.3) | 39.8 (29.3–52.4) | 1.70 (1.17–2.47) |
Non-STEMI | 282 | 1138 | 29.2 (26.0–37.8) | 47.9 (30.9–68.3) | 1.74 (1.07–2.83) |
MI unspecified | 209 | 722 | 33.5 (29.2–38.3) | 48.7 (36.0–63.1) | 1.27 (0.84–1.91) |