Table 1 Specification of the research question applying a PICO (population, intervention, comparison and outcome) model
From: Fenoldopam to prevent acute kidney injury after major surgery—a systematic review and meta-analysis
Population | Intervention | Comparison | Outcomes |
|---|---|---|---|
Adult patients (≥18 years) undergoing any type of major surgery | Treatment with fenoldopam in the peri-operative period | Placebo | Incidence of AKI Requirement for RRT post-operatively Hospital mortality Side effects (hypotension, need for catecholamine treatment) |