|
Variable
|
Healthy controls
|
No shock
|
Shock
|
p value
|
|---|
|
n = 32
|
n = 33
|
n = 29
|
|---|
|
Mean age (years) ± SD
|
40 ± 16
|
56 ± 18
|
58 ± 21
|
0.0002
|
|
Male gender (%)
|
15 (44)
|
15 (45)
|
22 (76)
|
0.03
|
|
White race (%)
|
28 (82)
|
19 (58)
|
16 (55)
|
0.01
|
|
Source of infection (%)
|
N/A
| | |
0.6
|
|
Urinary tract
| |
11 (33)
|
9 (31)
| |
|
Pneumonia
| |
9 (27)
|
12 (41)
| |
|
Intravascular device
| |
5 (15)
|
2 (7)
| |
|
Other
| |
7 (21)
|
6 (21)
| |
|
Organism (%)
|
N/A
| | |
0.28
|
|
Gram-negative bacteria
| |
12 (36)
|
11 (38)
| |
|
Gram-positive bacteria
| |
5 (15)
|
3 (10)
| |
|
Unknown
| |
11 (33)
|
6 (21)
| |
|
Other
| |
4 (12)
|
9 (31)
| |
|
Mechanical ventilation (%)
|
N/A
|
12 (36)
|
14 (48)
|
0.28
|
|
ARDS (%)
|
N/A
|
5 (15 %)
|
9 (7 %)
|
0.22
|
|
Acute kidney injury (%)
|
N/A
|
20 (61 %)
|
18 (62 %)
|
0.79
|
|
Mean APACHE II score ± SD
|
N/A
|
20.5 ± 7.4
|
23.5 ± 8.3
|
0.09
|
|
Median ICU LOS in days (IQR)
|
N/A
|
2 (7)
|
4 (4)
|
0.16
|
|
Median hospital LOS in days (IQR)
|
N/A
|
7 (11)
|
7 (12)
|
0.64
|
|
Death (%)
|
N/A
|
3 (9)
|
9 (31)
|
0.03
|
-
SD standard deviation, N/A not applicable, ARDS acute respiratory distress syndrome, APACHE acute physiology and chronic health evaluation, ICU intensive care unit, LOS length of stay, IQR interquartile range
