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Table 3 Acid–base parameters and electrolytes before and after ECAD

From: Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure – a prospective, randomised crossover study

 

MARS, median (IQR)

SPAD, median (IQR)

 

Pre-ECAD

Post-ECAD

Difference

Pre-ECAD

Post-ECAD

Difference

pH

7.42 (7.374–7.447)

7.42 (7.390–7.449)

n.s.

7.40 (7.356–7.424)

7.43 (7.386–7.454)

*

SBC, mmol/L

27.3 (24.03–31.48)

27.5 (24.70–30.60)

n.s.

25.1 (22.75–27.50)

27.8 (24.45–30.60)

*

Base excess, mmol/L

3.9 (0.03–8.35)

3.8 (0.70–7.20)

n.s.

1.3 (−1.40/+3.85)

4.0 (0.40/7.65)

*

Lactate, mmol/L

1.9 (1.30–2.70)

2.1 (1.70–3.00)

*

1.8 (1.30–2.75)

2.5 (1.70–3.60)

*,**

Sodium, mmol/L

142 (138.3–146.0)

143 (139.0–147.0)

n.s.

141 (136.5–146.0)

144 (139.0–148.5)

*,**

Potassium, mmol/L

4.5 (4.20–4.70)

4.2 (3.90–4.60)

*

4.4 (4.15–4.70)

4.2 (3.90–4.60)

*

Calcium, mmol/L

1.24 (1.140–1.330)

1.15 (1.090–1.260)

*

1.21 (1.115–1.310)

1.06 (0.890–1.145)

*,**

Glucose, mmol/L

6.9 (5.70–8.00)

7.3 (6.15–8.05)

n.s.

6.6 (6.00–7.80)

7.5 (6.50–8.80)

*

Osmolality, mOsmol/kg H2O

305.1 (295.85–320.79)

305.7 (297.24–319.79)

n.s.

304.5 (294.53–312.01)

310.1 (299.76–319.85)

*,**

  1. ECAD extracorporeal albumin dialysis, MARS Molecular Adsorbents Recirculating System, SPAD single-pass albumin dialysis, SBC standard bicarbonate, IQR interquartile range, n.s. non-significant
  2. *p < 0.05 significant changes within ECAD
  3. **p < 0.05 significant differences between both devices