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Table 1 Patient characteristics

From: The leukocyte-stiffening property of plasma in early acute respiratory distress syndrome (ARDS) revealed by a microfluidic single-cell study: the role of cytokines and protection with antibodies

Characteristics

Healthy (n = 5)

ACPE (n = 6)

Mild ARDS (n = 9)

Moderate/severe ARDS (n = 13)

Age, yr

38 [34–43]

72 [68–82]

57 [42–71]

58 [56–76]

Sex, M/F, n

2/3

3/3

4/5

9/4

Septic shock, n

–

–

5

10

SAPS II at admission

–

24 [21–26]

52 [49–57]

53 [46–57]

PaO2/FiO2,a mmHg

–

145 [130–201]

220 [202–223]

105 [98–122]

PEEP,a mmHg

–

5 [5–7]

5 [5–7]

8 [8–12]

Lung Injury Scorea

–

–

1.5 [1.25–1.75]

2.25 [2–2.25]

Causes of ARDS/ALI, n

    

 Direct

–

–

6

8

  Pneumonia

  

5

7

  Gastric inhalation

  

1

1

 Indirect

–

–

3

5

  Pancreatitis

  

2

2

  Intra-abdominal infection

  

1

3

  1. ACPE acute cardiogenic pulmonary edema, ALI acute lung injury, ARDS acute respiratory distress syndrome, FiO 2 fraction of inspired oxygen, PaO 2 partial pressure of oxygen in arterial blood, PEEP positive end-expiratory pressure, SAPS II Simplified Acute Physiology Score II
  2. Results are expressed as median [IQR] unless otherwise indicated
  3. aLower PaO2/FiO2 ratio during the first 48 h