Fig. 1
From: PEEP titration during prone positioning for acute respiratory distress syndrome
Comparison of set PEEP used in proning clinical trials and hypothetical PEEP that would have been required under the ALVEOLI or LOVS high-PEEP protocols. Expected PEEP under high-PEEP protocols was calculated by using individual patient FiO2 values. When the study protocol permitted multiple PEEP levels for a given FiO2, the lowest PEEP value was chosen to bias results toward smaller difference between set and expected PEEP. a Baseline PEEP values prior to study intervention. b First post-intervention PEEP values. Column height and error bars represent mean and standard deviation, respectively. #Significantly different than set PEEP at P < 0.05. ALVEOLI ARDS Network Assessment of Low tidal Volume and elevated End-expiratory volume to Obviate Lung Injury Trial, FiO2 fraction of inspired oxygen, LOVS Lung Open Ventilation Study, PEEP positive end-expiratory pressure