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Table 1 Lipophilicity and protein binding characteristics of study drugs

From: Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models

Study drug Lipophilicity (logP) Protein binding (%)
Ceftriaxone −1.7 95
Ciprofloxacin 2.3 20–40
Caspofungin 0.1 97
Fluconazole 0.4 11–12
Gentamicin −3.1 0–30
Meropenem −0.6 2
Doripenem 0.7 8
Vancomycin −3.1 55
  1. A higher numeric value for octanol-water partition coefficient (logP) indicates greater lipophilicity [29]