Table 4 Neutrophil, lymphocyte, and NLCR variations from admission to day 5 in late survivors and late nonsurvivors
From: Reversal of neutrophil-to-lymphocyte count ratio in early versus late death from septic shock
Survivors after day 5 (n = 49) | Late death after day 5 (n = 21) | p Value | |
|---|---|---|---|
Age, yr | 72.5 (61.6–79.3) | 77.9 (64.4–85.7) | 0.2 |
Female | 16 (32.7) | 9 (42.9) | 0.41 |
Male | 33 (67.3) | 12 (57.1) | |
Comorbidities | |||
CAD | 12 (24.5) | 3 (14.3) | 0.34 |
Diabetes | 11 (22.4) | 7 (33.3) | 0.34 |
COPD | 7 (14.3) | 2 (9.5) | 0.59 |
Cancer/immunosuppression | 10 (20.4) | 6 (28.6) | 0.46 |
Charlson comorbidity index score | 5 (3–6) | 5 (4–7) | 0.66 |
Severity and outcome | |||
SAPS II | 48 (42–56) | 55 (49–61) | 0.083 |
SOFA score at admission | 9 (6–10) | 8 (6–9) | 0.58 |
In-ICU LOS | 10 (7–18) | 14 (10–22) | 0.15 |
Hospital-acquired infection | 12 (24.5) | 14 (66.7) | 0.00082 |
Cell counts at admission | |||
Neutrophils, 109/L | 8.2 (5.5–16.1) | 10.9 (6.1–13.2) | 0.68 |
Lymphocytes, 109/L | 0.7 (0.5–1.1) | 1.2 (0.9–2) | 0.0012 |
NLCR | 11.8 (6.6–18.3) | 7 (4–12.9) | 0.06 |
Cell counts at day 5 | |||
Neutrophils, 109/L | 9.2 (6.7–11.8) | 16.4 (13.3–24.2) | 0.0001 |
Lymphocytes, 109/L | 1 (0.8–1.3) | 1 (0.7–1.3) | 0.89 |
NLCR | 9.1 (6.7–12.5) | 12.8 (8.4–35.4) | 0.028 |
Cell counts variations from day 1 to day 5 | |||
Neutrophils, % | 6.3 (−47.2 to 75.3) | 50.5 (3.4 to 207.0) | 0.026 |
Lymphocytes, % | 33.3 (−20.0 to 141.7) | −21.8 (−43.2 to 44.6) | 0.034 |
NLCR, % | −20.0 (−57.4 to 45.9) | 34.8 (−8.2 to 305.4) | 0.003 |