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Fig. 1 | Critical Care

Fig. 1

From: Biomarker validity in the critically ill: all must face the (continuous) renal replacement challenge!

Fig. 1

OPN serum levels are elevated in critically ill patients with RRT. a OPN serum concentrations at day 3 of medical ICU treatment were significantly higher (P < 0.001, U test) in patients that received RRT (n = 34) compared with patients without need for this therapy (n = 78). b, c Patients with a need for RRT displayed a significantly impaired ICU survival and overall survival in comparison with other patients, based on Kaplan–Meier curve analysis. ***P <0.001. RRT Renal replacement therapy

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