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Table 3 Arterial blood gas analysis in part I of the experiment

From: Effects of different types of fluid resuscitation for hemorrhagic shock on splanchnic organ microcirculation and renal reactive oxygen species formation

 

T0

T1

T2

ANOVA group effects

ANOVA time effects

ANOVA group-time interaction

Baseline

Completion of shock

End of experiment

pH

   

p = 0.520

p = 0.032

p = 0.527

Control

7.38 (7.36-7.40)

7.36 (7.31-7.38)

7.37 (7.34-7.44)

NS

7.40 (7.39-7.42)

7.38 (7.34-7.39)

7.42 (7.40-7.44)

HTS

7.38 (7.37-7.40)

7.36 (7.35-7.38)

7.39 (7.31-7.39)

GEL

7.38 (7.35-7.40)

7.34 (7.30-7.36)

7.36 (7.32-7.39)

HES

7.39 (7.38-7.41)

7.35 (7.31-7.37)

7.40 (7.37-7.42)

PaO2/FiO2

   

p = 0.182

p = 0.168

p = 0.738

Control

481 (439–499)

390 (378–444)

430 (350–458)

NS

421 (384–468)

425 (391–470)

442 (376–467)

HTS

472 (454–490)

464 (410–486)

485 (450–533)

GEL

434 (431–456)

421 (385–458)

426 (380–510)

HES

412 (399–466)

399 (344–467)

413 (386–478)

PaCO2 (mmHg)

   

p = 0.491

p = 0.484

p = 0.351

Control

38.4 (37.4-40.4)

36.1 (34.7-44.9)

34.2 (27.9-34.5)

NS

37.7 (36.7-39.6)

36.3 (33.8-41.9)

34.3 (31.2-37.7)

HTS

38.7 (37.2-40.4)

38.1 (35.6-40.6)

36.8 (35.5-39.5)

GEL

38.0 (32.3-39.3)

37.8 (34.8-39.4)

39.0 (35.6-43.1)

HES

39.7 (39.4-41.1)

34.4 (30.9-44.8)

37.3 (37.0-47.0)

Hemoglobin (g/dL)

   

p = 0.021

p < 0.001

p = 0.098

Control

13.0 (12.5-13.8)

9.5 (9.4-10.0)

10.0 (8.6-10.2)

NS

12.6 (12.4-12.9)

10.1 (7.2-10.9)

9.1 (8.5-9.4)

HTS

12.4 (11.8-12.6)

9.8 (9.2-10.4)

8.5 (8.4-9.0)

GEL

12.6 (12.3-13.4)

10.0 (9.9-10.6)

11.2 (8.8-12.4)*

HES

12.4 (12.0-12.8)

10.1 (9.6-10.9)

8.8 (8.3-9.3)

Hematocrit (%)

   

p = 0.021

p <0.001

p = 0.120

Control

39 (38–41)

29 (28–30)

30 (26–30)

NS

38 (37–39)

30 (22–33)

27 (25–29)

HTS

37 (35–38)

29 (27–32)

26 (25–27)

GEL

38 (37–38)

30 (30–32)

34 (27–37)

HES

38 (36–39))

30 (29–33)

27 (25–28)

Lactate (mmol/L)

   

p = 0.026

p <0.001

p <0.001

Control

0.6 (0.5-0.9)

4.4 (3.8-5.0)

4.3 (3.0-5.8)

NS

1.0 (1.0-1.3)

4.3 (4.0-5.0)

2.0 (1.8-2.6)*

HTS

0.9 (0.8-1.4)

4.6 (3.0-5.6)

1.7 (1.6-2.2)*

GEL

1.2 (0.9-1.5)

3.5 (2.3-4.5)

1.2 (1.0-1.7)*

HES

1.3 (1.0-1.3)

3.3 (3.1-4.1)

1.9 (1.3-2.4)*

  1. Data are median (interquartile range). *Value significantly different to the control group with p <0.05. ANOVA analysis of variance, T time, NS 0.9 % saline, HTS hypertonic saline, HES hydroxyethyl starch, GEL gelatin, PaO2/FiO2 ratio of arterial partial pressure of oxygen/inspired oxygen fraction, PaCO2 arterial partial pressure of carbon dioxide