| T0 | T1 | T2 | ANOVA group effects | ANOVA time effects | ANOVA group-time interaction |
---|---|---|---|---|---|---|
Baseline | Completion of shock | End of experiment | ||||
pH |  |  |  | p = 0.520 | p = 0.032 | p = 0.527 |
Control | 7.38 (7.36-7.40) | 7.36 (7.31-7.38) | 7.37 (7.34-7.44) | |||
NS | 7.40 (7.39-7.42) | 7.38 (7.34-7.39) | 7.42 (7.40-7.44) | |||
HTS | 7.38 (7.37-7.40) | 7.36 (7.35-7.38) | 7.39 (7.31-7.39) | |||
GEL | 7.38 (7.35-7.40) | 7.34 (7.30-7.36) | 7.36 (7.32-7.39) | |||
HES | 7.39 (7.38-7.41) | 7.35 (7.31-7.37) | 7.40 (7.37-7.42) | |||
PaO2/FiO2 |  |  |  | p = 0.182 | p = 0.168 | p = 0.738 |
Control | 481 (439–499) | 390 (378–444) | 430 (350–458) | |||
NS | 421 (384–468) | 425 (391–470) | 442 (376–467) | |||
HTS | 472 (454–490) | 464 (410–486) | 485 (450–533) | |||
GEL | 434 (431–456) | 421 (385–458) | 426 (380–510) | |||
HES | 412 (399–466) | 399 (344–467) | 413 (386–478) | |||
PaCO2 (mmHg) |  |  |  | p = 0.491 | p = 0.484 | p = 0.351 |
Control | 38.4 (37.4-40.4) | 36.1 (34.7-44.9) | 34.2 (27.9-34.5) | |||
NS | 37.7 (36.7-39.6) | 36.3 (33.8-41.9) | 34.3 (31.2-37.7) | |||
HTS | 38.7 (37.2-40.4) | 38.1 (35.6-40.6) | 36.8 (35.5-39.5) | |||
GEL | 38.0 (32.3-39.3) | 37.8 (34.8-39.4) | 39.0 (35.6-43.1) | |||
HES | 39.7 (39.4-41.1) | 34.4 (30.9-44.8) | 37.3 (37.0-47.0) | |||
Hemoglobin (g/dL) |  |  |  | p = 0.021 | p < 0.001 | p = 0.098 |
Control | 13.0 (12.5-13.8) | 9.5 (9.4-10.0) | 10.0 (8.6-10.2) | |||
NS | 12.6 (12.4-12.9) | 10.1 (7.2-10.9) | 9.1 (8.5-9.4) | |||
HTS | 12.4 (11.8-12.6) | 9.8 (9.2-10.4) | 8.5 (8.4-9.0) | |||
GEL | 12.6 (12.3-13.4) | 10.0 (9.9-10.6) | 11.2 (8.8-12.4)* | |||
HES | 12.4 (12.0-12.8) | 10.1 (9.6-10.9) | 8.8 (8.3-9.3) | |||
Hematocrit (%) |  |  |  | p = 0.021 | p <0.001 | p = 0.120 |
Control | 39 (38–41) | 29 (28–30) | 30 (26–30) | |||
NS | 38 (37–39) | 30 (22–33) | 27 (25–29) | |||
HTS | 37 (35–38) | 29 (27–32) | 26 (25–27) | |||
GEL | 38 (37–38) | 30 (30–32) | 34 (27–37) | |||
HES | 38 (36–39)) | 30 (29–33) | 27 (25–28) | |||
Lactate (mmol/L) |  |  |  | p = 0.026 | p <0.001 | p <0.001 |
Control | 0.6 (0.5-0.9) | 4.4 (3.8-5.0) | 4.3 (3.0-5.8) | |||
NS | 1.0 (1.0-1.3) | 4.3 (4.0-5.0) | 2.0 (1.8-2.6)* | |||
HTS | 0.9 (0.8-1.4) | 4.6 (3.0-5.6) | 1.7 (1.6-2.2)* | |||
GEL | 1.2 (0.9-1.5) | 3.5 (2.3-4.5) | 1.2 (1.0-1.7)* | |||
HES | 1.3 (1.0-1.3) | 3.3 (3.1-4.1) | 1.9 (1.3-2.4)* |