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Table 1 Microcirculatory blood flow intensity changes after hemorrhagic shock and fluid resuscitation in part I of the experiment

From: Effects of different types of fluid resuscitation for hemorrhagic shock on splanchnic organ microcirculation and renal reactive oxygen species formation

Flux

T0

T1

T2

ANOVA group effects

ANOVA time effects

ANOVA group-time interaction

Baseline

Completion of shock

End of experiment

Liver

   

p = 0.375

p <0.001

p = 0.132

Sham

1176 (1064–1245)

1147 (1091–1233)

1048 (938–1210)

Control

1115 (1052–1316)

856 (796–1203)

1082 (849–1095)

NS

1314 (1148–1365)

1026 (854–1116)

1174 (1136–1304)

HTS

1230 (1177–1317)

1027 (897–1200)

1019 (938–1239)

GEL

1095 (1063–1166)

922 (828–1033)

1111 (1027–1185)

HES

1250 (1044–1339)

898 (826–960)

1181 (1029–1228)

Kidney

   

p = 0.012

p <0.001

p <0.001

Sham

1653 (1443–1708)

1596 (1490–1712)

1479 (1458–1539)

Control

1476 (1260–1619)

894 (774–1104)***

1041 (673–1295)***

NS

1604 (1581–1821)

1071 (805–1228)***

1503 (1296–1617)*

HTS

1603 (1570–1695)

1116 (974–1283)***

1413 (1171–1645)*

GEL

1601 (1429–1642)

1093 (860–1211)***

1687 (1448–1862)*

HES

1537 (1132–1709)

1062 (857–1253)***

1478 (1195–1596)*

Mucosa

   

p < 0.001

p < 0.001

p < 0.001

Sham

1422 (1238–1700)

1259 (1189–1332)

1150 (960–1187)

Control

144 (1244–1749)

441 (404–668)***

398 (366–434)***

NS

1913 (1737–2112)

631 (387–831)***

763 (728–872)*, ***

HTS

1732 (1552–1978)

599 (507–895)***

950 (858–1123)*

GEL

2015 (1723–2130)

768 (620–802)***

980 (867–1061)*

HES

1682 (1393–1872)

567 (520–817)***

950 (818–1247)*

Serosa

   

p = 0.010

p <0.001

p <0.001

Sham

933 (903–986)

1133 (920–1215)

937 (675–1306)

Control

950 (803–1003)

446 (349–681)***

369 (267–704)***

NS

1049 (901–1090)

563 (441–646)***

669 (653–759)***

HTS

1002 (840–1080)

612 (460–692)***

1063 (809–1456)*, **

GEL

887 (863–1016)

568 (477–691)***

804 (725–1058)*

HES

854 (850–1031)

526 (426–659)***

759 (628–1017)*

Peyer’s patch

   

p = 0.002

p <0.001

p <0.001

Sham

1513 (1220–1941)

1511 (1220–1941)

1328 (1146–1563)

Control

1149 (1052–1318)

616 (421–636)***

548 (436–668)***

NS

1530 (1261–1740)

581 (348–907)***

916 (718–1040)*, ***

HTS

1603 (1549–1739)

838 (655–999)***

1223 (1046–1441)*

GEL

1578 (1309–1725)

655 (607–875)***

1075 (919–1080)*

HES

1525 (1443–1669)

791 (634–934)***

1209 (837–1513)*

Gracilis muscle

   

p = 0.108

p = 0.018

p <0.001

Sham

941 (928–999)

989 (868–1371)

1091 (857–1367)

Control

897 (856–1087)

841 (641–1066)

721 (634–797)

NS

991 (904–1190)

967 (791–1268)

975 (869–1140)

HTS

1020 (932–1175)

950 (766–1025)

967 (866–1131)

GEL

1009 (884–1077)

1008 (853–1147)

953 (877–1252)

HES

1064 (904–1223)

1302 (1152–1397)

798 (695–1044)

  1. Data are median (interquartile range). *Value in the fluid resuscitation group significantly different to control group with p <0.05. **Value in fluid resuscitation group significantly different to 0.9 % saline group with p <0.05. ***Value in fluid resuscitation or control significantly different to sham group with p <0.05. ANOVA analysis of variance, T time, NS 0.9 % saline, HTS hypertonic saline, HES hydroxyethyl starch, GEL gelatin