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Table 1 Characteristics of the studies included in the meta-analysis

From: Association between the TLR2 Arg753Gln polymorphism and the risk of sepsis: a meta-analysis

Study

Country

Ethnicity

Age group

Sepsis type

Source of control subjects

Sample size

Case polymorphisms

Control polymorphisms

HWE

      

Cases

Controls

GG

GA

AA

GG

GA

AA

 

Schnetzke et al., 2015 [21]

Germany

European

Adult

Sepsis

Patients with acute myeloid leukemia

74

81

66

7

1

79

2

0

Yes

Tellería-Orriols et al., 2014 [22]

Spain

European

Pediatric

Sepsis

Healthy

153

66

61

72

20

49

15

2

Yes

Nachtigall et al., 2014 [23]

Germany

European

Adult

Mix

Critically ill patients

98

47

88

10

0

47

0

0

Yes

Bronkhorst, et al., 2013 [24]

The Netherlands

European

Adult

Sepsis

Critically ill patients

79

140

74

5

0

130

10

0

Yes

Lee et al., 2011 [25]

United States

European

Adult

Mix

Patients after liver transplant

187

405

169

15

3

366

27

12

No

Ahmad-Nejad et al., 2011 [26]

Germany

European

Adult

Mix

Critically ill patients

38

112

34

4

0

107

5

0

Yes

Shan et al., 2010 [27]

China

Han Chinese

Pediatric

Severe sepsis

Healthy

38

57

36

2

0

57

0

0

Yes

Davis et al., 2010 [31]

United States

European

Adult

Sepsis

Healthy

24

53

19

5

0

48

5

0

Yes

Yuan et al., 2008 [28]

Australia

Mix

Pediatric

Sepsis

Healthy

85

409

82

3

0

382

27

0

Yes

McDaniel et al., 2007 [29] (study 2)

United States

European

Adult

Sepsis

Critically ill patients

15

21

12

3

0

17

4

0

Yes

McDaniel et al., 2007 [29] (study 1)

United States

African

Adult

Sepsis

Critically ill patients

16

16

6

10

0

12

4

0

Yes

Lorenz et al., 2000 [30]

France

European

Adult

Septic shock

Healthy

91

110

89

2

0

107

3

0

Yes

  1. HWE Hardy-Weinberg equilibrium