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Fig. 3 | Critical Care

Fig. 3

From: Brief inhalation of nitric oxide increases resuscitation success and improves 7-day-survival after cardiac arrest in rats: a randomized controlled animal study

Fig. 3

Alterations in mean atrial pressure (MAP), lactate levels and base excess before cardiac arrest and after return of spontaneous circulation (ROSC). The decrease in MAP and concurrent increase in lactate was significantly less pronounced in animals treated with 20 ppm inhaled nitric oxide (iNO) in comparison to controls. Inhalation of NO attenuated the decrease in base excess, being significant in animals that received 20 ppm iNO in comparison to controls. P <0.05 for 20 ppm iNO vs. control; mean ± standard error of the mean. Data based on 10 animals in each group at baseline (BL). All other time points: 20 ppm, n = 10; 40 ppm, n = 6; Control, n = 7. PR post return of ROSC

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