Fig. 1

Fractalkine levels are elevated in sepsis and correlate with organ failure. Blood was drawn from patients within 24 hours of admission to the ICU (day 0) and on days 2 and 4. a Fractalkine levels were elevated in patients compared to healthy volunteers (HV) at all time points, and did not differ between days 0 and 4. b Fractalkine levels were not influenced by the primary source of infection. c Admission fractalkine levels in patients with increasing numbers of failing organs at admission. Fractalkine levels were higher in patients with shock on admission (d) and in patients who developed shock >24 hours after admission (e). Box and whisker diagrams depict the median and lower quartile, upper quartile, and their respective 1.5 IQR as whiskers (as specified by Tukey). Gray boxes represent sepsis; open box or dotted lines represent healthy volunteers. ***P <0.001, *P <0.05