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Table 2 Haemodynamic variables and intra-abdominal pressure at different study times

From: Effects of passive leg raising and volume expansion on mean systemic pressure and venous return in shock in humans

 

Baseline

During passive leg raising

P vs. baseline

After volume expansion

P vs. baseline

Heart rate, beats/mm

 Fluid responders

92 ± 16

94 ± 17

0.07

94 ± 15

0.23

 Fluid nonresponders

80 ± 21

79 ± 21

0.29

79 ± 19

0.07

Mean arterial pressure, mm Hg

 Fluid responders

67 ± 9

74 ± 10

0.07

76 ± 13

0.04

 Fluid nonresponders

79 ± 13

81 ± 20

0.67

83 ± 14

0.13

Mean systemic pressure, mm Hg

 Fluid responders

25 ± 13

31 ± 13

<0.01

32 ± 17

<0.01

 Fluid nonresponders

24 ± 10

27 ± 10

<0.01

28 ± 12

<0.01

Cardiac index, L/mm/m2

 Fluid responders

2.8 ± 0.9

3.2 ± 0.8

<0.01

3.6 ± 1.1

<0.01

 Fluid nonresponders

2.9 ± 1.1

3.0 ± 1.1

0.07

3.0 ± 1.3

0.07

Central venous pressure, mm Hg

 Fluid responders

7 ± 3

9 ± 4

<0.01

9 ± 4

<0.01

 Fluid nonresponders

8 ± 4

11 ± 4

<0.01

11 ± 4

<0.01

Inverse of the slope of venous return curve, mmHg.min.m2/L

 Fluid responders

6.4 ± 3.7

6.8 ± 3.1

0.54

7.0 ± 5.4

0.35

 Fluid nonresponders

5.9 ± 3.8

5.7 ± 3.7

0.75

6.0 ± 3.9

0.84

Resistance to venous return, mmHg.min.m2/L

 Fluid responders

6.6 ± 3.5

6.8 ± 4.5

0.66

6.6 ± 4.9

0.93

 Fluid nonresponders

5.6 ± 3.5

5.7 ± 3.3

0.65

6.1 ± 4

0.22

Mean systemic pressure - central venous pressure gradient, mmHg

 Fluid responders

19 ± 12

22 ± 12

0,02

23 ± 15

0,02

 Fluid nonresponders

16 ± 9

16 ± 9

0.62

17 ± 11

0.33

Intra-abdominal pressure, mm Hg

 Fluid responders

12 ± 6

12 ± 6

1,00

13 ± 6

0.42

 Fluid nonresponders

16 ± 5

14 ± 5

0.09

16 ± 6

0.55

  1. Values are expressed as mean ± standard deviation