Table 1 Results of clinical and biological heparin-induced thrombocytopenia (HIT) diagnosis evaluation
From: Argatroban in the management of heparin-induced thrombocytopenia: a multicenter clinical trial
Patient | HIT experts opinion | « 4T » score | Polyspecific (IgG, IgA or IgM) ELISA OD/cutoff | Platelet aggregation | Serotonin release assay | |
|---|---|---|---|---|---|---|
1 | Confirmed | 5 | 1.72/0.52 | Positive | Positive | n.a. |
2 | Confirmed | 5 | 2.97/0.51 | Positive | Negative | n.a. |
3 | Confirmed | 7 | 2.73/0.51 | Positive | Positive | n.a. |
4 | Confirmed | 7 | 3.09/0.46 | Positive | Positive | n.a. |
5 | Confirmed | 4 | >2.5/0.5 | Positive | Negative | Positive |
6 | Confirmed | 6 | 2.5/0.5 | Positive | n.a. | Positive |
7 | Not confirmed | 5 | 0.37/0.7 | Negative | n.a. | n.a. |
8 | Not confirmed | 5 | 0.18/0.12 | Positive | n.a. | Inconclusive |
9 | Confirmed | 8 | 1.56/0.4 | Positive | n.a. | Positive |
10 | Confirmed | 4 | 2.77/0.46 | Positive | Positive | n.a. |
11 | Confirmed | 7 | 0.84/0.38 | Positive | Inconclusive | n.a. |
12 | Confirmed | 6 | 1.89/0.47 | Positive | Positive | n.a. |
13 | Confirmed | 6 | 0.17/0.48 | Negative | Positive | n.a. |
14 | Confirmed | 5 | 0.93/0.43 | Positive | Positive | n.a. |
15 | Confirmed | 5 | 2.68/0.45 | Positive | Positive | n.a. |
16 | Not confirmed | 5 | 0.06/0.43 | Negative | Negative | n.a. |
17 | Confirmed | 5 | 2.41/0.46 | Positive | Positive | n.a. |
18 | Not confirmed | 6 | 0.08/0.43 | Negative | Negative | n.a. |
19 | Confirmed | 6 | 3.12/0.61 | Positive | Positive | n.a. |
20 | Confirmed | 6 | 3.31/0.45 | Positive | Inconclusive | n.a. |