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Table 3 Prevalence of extracorporeal therapy use and mortality by age, co-morbidity, and organ dysfunction

From: Extracorporeal therapies in pediatric severe sepsis: findings from the pediatric health-care information system

Characteristic

ECMO alone (N = 1358)

RRT alone (N = 2937)

ECMO + RRT (N = 500)

Prevalence

Mortality

Prevalence

Mortality

Prevalence

Mortality

Age

 <1 year

661 (48.7 %)

344 (52.0 %)

368 (12.5 %)

144 (39.1 %)

169 (33.8 %)

111 (65.7 %)

 1-4 years

319 (23.5 %)

130 (40.8 %)

681 (23.2 %)

197 (28.9 %)

102 (20.4 %)

61 (59.8 %)

 5-9 years

126 (9.3 %)

57 (45.2 %)

465 (15.8 %)

133 (28.6 %)

66 (13.2 %)

27 (40.9 %)

 10-18 years

252 (18.6 %)

118 (46.8 %)

1423 (48.5 %)

474 (33.3 %)

163 (32.6 %)

91 (55.8 %)

Co-morbidity

 Any condition

1100 (81.0 %)

522 (47.5 %)

2289 (77.9 %)

806 (35.2 %)

356 (71.2 %)

206 (71.0 %)

 Neurologic

156 (11.5 %)

57 (36.5 %)

382 (13.0 %)

113 (29.6 %)

42 (8.4 %)

21 (50.0 %)

 Cardiovascular

885 (65.2 %)

404 (45.7 %)

615 (20.9 %)

261 (42.4 %)

234 (46.8 %)

135 (57.7 %)

 Respiratory

122 (9.0 %)

50 (41.0 %)

107 (3.6 %)

52 (48.6 %)

34 (6.8 %)

25 (73.5 %)

 Renal

59 (4.3 %)

31 (52.5 %)

675 (23.0 %)

129 (13.6 %)

33 (6.6 %)

18 (54.6 %)

 Gastroenterology

46 (3.4 %)

23 (50.0 %)

240 (8.2 %)

107 (44.6 %)

18 (3.6 %)

13 (72.2 %)

 Hematology/Immunology

105 (7.7 %)

57 (54.3 %)

313 (10.7 %)

144 (15.2 %)

34 (6.8 %)

21 (61.8 %)

 Metabolic disorder

132 (9.7 %)

61 (46.2 %)

769 (26.2 %)

210 (27.3 %)

75 (15.0 %)

38 (50.7 %)

 Malignancy

82 (6.0 %)

52 (63.4 %)

723 (24.6 %)

381 (52.7 %)

50 (10.0 %)

29 (58.0 %)

 Other

183 (13.5 %)

94 (51.4 %)

201 (6.8 %)

63 (31.3 %)

33 (6.6 %)

22 (66.7 %)

 None

258 (19.0 %)

127 (49.2 %)

648 (22.1 %)

142 (21.9 %)

144 (28.8 %)

84 (58.3 %)

Organ dysfunction

 1

241 (17.8 %)

122 (50.6 %)

683 (23.3 %)

82 (12.0 %)

45 (9.0 %)

27 (60.0 %)

 2

646 (47.6 %)

264 (40.9 %)

948 (32.3 %)

299 (31.5 %)

185 (37.0 %)

102 (55.1 %)

 3

309 (22.8 %)

163 (52.8 %)

725 (24.7 %)

302 (41.7 %)

153 (30.6 %)

89 (58.2 %)

 4

117 (8.6 %)

72 (61.5 %)

406 (13.8 %)

182 (44.8 %)

88 (17.6 %)

52 (59.1 %)

 5+

45 (3.3 %)

28 (62.2 %)

175 (6.0 %)

83 (47.4 %)

29 (5.8 %)

20 (69.0 %)

  1. ECMO extracorporeal membrane oxygenation, RRT Renal replacement therapy