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Table 1 Demographics of patients with pediatric severe sepsis on extracorporeal therapy

From: Extracorporeal therapies in pediatric severe sepsis: findings from the pediatric health-care information system

All patients from 2004 to 2012

Any ET

ECMO

RRT

N = 49,153 PSS cases

Use in PSS, N (%)

4795 (9.8 %)

1858 (3.8 %)

3437 (7.0 %)

Gender, N (%)

 Male

2452 (51.2 %)

978 (52.7 %)

1728 (50.3 %)

 Female

2342 (48.8 %)

879 (47.3 %)

1709 (49.7 %)

Age group at admission, N (%)

 <1 year

1198 (25.0 %)

830 (44.7 %)

537 (15.6 %)

 1–4 years

1102 (23.0 %)

421 (22.7 %)

783 (22.8 %)

 5–9 years

657 (13.7 %)

192 (10.3 %)

531 (15.5 %)

 10–18 years

1838 (38.3 %)

415 (22.3 %)

1586 (46.1 %)

Total hospitalization, days

 Median (25 %–75 %)

34 (17–64)

35 (16–67)

34 (17–62)

ICU, days

 Median (25 %–75 %)

19 (8–38)

25 (12–48)

17 (7–34)

Co-morbidities, N (%)

 Any condition

3745 (78.1 %)

1,456 (78.4 %)

2645 (77.0 %)

 Neurologic

580 (12.1 %)

198 (10.7 %)

424 (12.3 %)

 Cardiovascular

1734 (36.2 %)

1119 (60.2 %)

849 (24.7 %)

 Respiratory

263 (5.5 %)

156 (8.4 %)

141 (4.1 %)

 Renal

767 (16.0 %)

92 (5.0 %)

708 (20.6 %)

 Gastroenterology

304 (6.3 %)

64 (3.4 %)

258 (7.5 %)

 Hematology/Immunology

452 (9.4 %)

139 (7.5 %)

347 (10.1 %)

 Metabolic disorder

976 (20.4 %)

207 (11.1 %)

844 (24.6 %)

 Malignancy

855 (17.8 %)

133 (7.1 %)

773 (22.5 %)

 Other

417 (8.7 %)

216 (11.6 %)

234 (6.8 %)

Acute organ dysfunction

Number of systems affected, N (%)

 1

969 (20.2 %)

286 (15.4 %)

728 (21.2 %)

 2

1779 (37.1 %)

831 (44.7 %)

1133 (33.0 %)

 3

1187 (24.8 %)

462 (24.9 %)

878 (25.6 %)

 4

611 (12.7 %)

205 (11.0 %)

494 (14.4 %)

 5+

249 (5.2 %)

74 (4.0 %)

204 (5.9 %)

  1. PSS pediatric severe sepsis, ET extracorporeal therapy, ECMO extracorporeal membrane oxygenation, RRT Renal replacement therapy