Table 1 Demographics of patients with pediatric severe sepsis on extracorporeal therapy
All patients from 2004 to 2012 | Any ET | ECMO | RRT |
|---|---|---|---|
N = 49,153 PSS cases | |||
Use in PSS, N (%) | 4795 (9.8 %) | 1858 (3.8 %) | 3437 (7.0 %) |
Gender, N (%) | |||
Male | 2452 (51.2 %) | 978 (52.7 %) | 1728 (50.3 %) |
Female | 2342 (48.8 %) | 879 (47.3 %) | 1709 (49.7 %) |
Age group at admission, N (%) | |||
<1 year | 1198 (25.0 %) | 830 (44.7 %) | 537 (15.6 %) |
1–4 years | 1102 (23.0 %) | 421 (22.7 %) | 783 (22.8 %) |
5–9 years | 657 (13.7 %) | 192 (10.3 %) | 531 (15.5 %) |
10–18 years | 1838 (38.3 %) | 415 (22.3 %) | 1586 (46.1 %) |
Total hospitalization, days | |||
Median (25 %–75 %) | 34 (17–64) | 35 (16–67) | 34 (17–62) |
ICU, days | |||
Median (25 %–75 %) | 19 (8–38) | 25 (12–48) | 17 (7–34) |
Co-morbidities, N (%) | |||
Any condition | 3745 (78.1 %) | 1,456 (78.4 %) | 2645 (77.0 %) |
Neurologic | 580 (12.1 %) | 198 (10.7 %) | 424 (12.3 %) |
Cardiovascular | 1734 (36.2 %) | 1119 (60.2 %) | 849 (24.7 %) |
Respiratory | 263 (5.5 %) | 156 (8.4 %) | 141 (4.1 %) |
Renal | 767 (16.0 %) | 92 (5.0 %) | 708 (20.6 %) |
Gastroenterology | 304 (6.3 %) | 64 (3.4 %) | 258 (7.5 %) |
Hematology/Immunology | 452 (9.4 %) | 139 (7.5 %) | 347 (10.1 %) |
Metabolic disorder | 976 (20.4 %) | 207 (11.1 %) | 844 (24.6 %) |
Malignancy | 855 (17.8 %) | 133 (7.1 %) | 773 (22.5 %) |
Other | 417 (8.7 %) | 216 (11.6 %) | 234 (6.8 %) |
Acute organ dysfunction | |||
Number of systems affected, N (%) | |||
1 | 969 (20.2 %) | 286 (15.4 %) | 728 (21.2 %) |
2 | 1779 (37.1 %) | 831 (44.7 %) | 1133 (33.0 %) |
3 | 1187 (24.8 %) | 462 (24.9 %) | 878 (25.6 %) |
4 | 611 (12.7 %) | 205 (11.0 %) | 494 (14.4 %) |
5+ | 249 (5.2 %) | 74 (4.0 %) | 204 (5.9 %) |