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Table 1 Demographics of patients with pediatric severe sepsis on extracorporeal therapy

From: Extracorporeal therapies in pediatric severe sepsis: findings from the pediatric health-care information system

All patients from 2004 to 2012 Any ET ECMO RRT
N = 49,153 PSS cases
Use in PSS, N (%) 4795 (9.8 %) 1858 (3.8 %) 3437 (7.0 %)
Gender, N (%)
 Male 2452 (51.2 %) 978 (52.7 %) 1728 (50.3 %)
 Female 2342 (48.8 %) 879 (47.3 %) 1709 (49.7 %)
Age group at admission, N (%)
 <1 year 1198 (25.0 %) 830 (44.7 %) 537 (15.6 %)
 1–4 years 1102 (23.0 %) 421 (22.7 %) 783 (22.8 %)
 5–9 years 657 (13.7 %) 192 (10.3 %) 531 (15.5 %)
 10–18 years 1838 (38.3 %) 415 (22.3 %) 1586 (46.1 %)
Total hospitalization, days
 Median (25 %–75 %) 34 (17–64) 35 (16–67) 34 (17–62)
ICU, days
 Median (25 %–75 %) 19 (8–38) 25 (12–48) 17 (7–34)
Co-morbidities, N (%)
 Any condition 3745 (78.1 %) 1,456 (78.4 %) 2645 (77.0 %)
 Neurologic 580 (12.1 %) 198 (10.7 %) 424 (12.3 %)
 Cardiovascular 1734 (36.2 %) 1119 (60.2 %) 849 (24.7 %)
 Respiratory 263 (5.5 %) 156 (8.4 %) 141 (4.1 %)
 Renal 767 (16.0 %) 92 (5.0 %) 708 (20.6 %)
 Gastroenterology 304 (6.3 %) 64 (3.4 %) 258 (7.5 %)
 Hematology/Immunology 452 (9.4 %) 139 (7.5 %) 347 (10.1 %)
 Metabolic disorder 976 (20.4 %) 207 (11.1 %) 844 (24.6 %)
 Malignancy 855 (17.8 %) 133 (7.1 %) 773 (22.5 %)
 Other 417 (8.7 %) 216 (11.6 %) 234 (6.8 %)
Acute organ dysfunction
Number of systems affected, N (%)
 1 969 (20.2 %) 286 (15.4 %) 728 (21.2 %)
 2 1779 (37.1 %) 831 (44.7 %) 1133 (33.0 %)
 3 1187 (24.8 %) 462 (24.9 %) 878 (25.6 %)
 4 611 (12.7 %) 205 (11.0 %) 494 (14.4 %)
 5+ 249 (5.2 %) 74 (4.0 %) 204 (5.9 %)
  1. PSS pediatric severe sepsis, ET extracorporeal therapy, ECMO extracorporeal membrane oxygenation, RRT Renal replacement therapy