Table 1 Physiological parameters at 6-hour end-point
From: Sepsis impairs microvascular autoregulation and delays capillary response within hypoxic capillaries
Variable | Sham (n = 6) | CLP (n = 5) | p value |
|---|---|---|---|
Weight (g) | 162 ± 3.3 | 164.5 ± 1.5 | NS |
Cardiovascular and blood gases | |||
Mean arterial pressure (mmHg) | 103.6 ± 2.9 | 68.8 ± 3.9 | <0.001 |
Arterial PO2 (mmHg) | 97.6 ± 5.4 | 108 ± 2.2 | NS |
Arterial SO2 (%) | 94.1 ± 2.5 | 92.7 ± 1.5 | NS |
Arterial pCO2 (mmHg) | 37.5 ± 2.9 | 34.9 ± 2.9 | NS |
pH | 7.43 ± 0.01 | 7.32 ± 0.03 | <0.001 |
Hemoglobin (g/dL) | 11.8 ± 0.3 | 14.9 ± 0.2 | <0.001 |
Plasma metabolites | |||
Lactate (μM) | 1.1 ± 0.1 | 2.1 ± 0.1 | <0.001 |
Arterial NOx (μM) | 18.1 ± 1.5 | 42.6 ± 4.1 | <0.001 |