|
Sociodemographics
|
|
Age, median (IQR)
|
62 (46, 76)
|
63 (47, 76)
|
69 (55, 81)
|
55 (38, 69)
|
|
Female gender, n (%)
|
3301 (46.7 %)
|
2046 (44.7 %)
|
500 (50.0 %)
|
755 (50.7 %)
|
|
Clinical presentation at ED admission, median (IQR)
|
|
Blood pressure diastolic (mmHg)
|
80 (70, 90)
|
81 (71, 91)
|
77.5 (67, 89)
|
79 (70, 90)
|
|
Blood pressure systolic (mmHg)
|
137 (121, 154)
|
138 (122, 155)
|
141 (121, 163)
|
133 (119, 149)
|
|
Confusion, n (%)
|
522 (7.3 %)
|
453 (9.9 %)
|
40 (4.0 %)
|
29 (1.9 %)
|
|
Pulse (bpm)
|
83 (71, 97)
|
82 (70, 95)
|
82 (71, 98)
|
86 (74, 99)
|
|
Respiratory rate (breaths/min)
|
18 (18, 20)
|
32 (24, 36)
|
18 (18, 20)
|
21 (18, 25)
|
|
SpO2 (%)
|
96.8 (94, 98)
|
96 (94, 97)
|
97 (95, 99)
|
98 (96, 99)
|
|
Temperature (°C),
|
36.8 (36.4, 37.2)
|
36.9 (36.6, 37.4)
|
36.5 (36.1, 36.8)
|
36.7 (36.4, 37)
|
|
Main symptom at ED admission, n (%)
|
|
Diarrhea, vomitus, dysuria
|
495 (6.9 %)
|
288 (6.3 %)
|
95 (9.5 %)
|
112 (7.2 %)
|
|
Fever
|
343 (4.8 %)
|
254 (5.5 %)
|
15 (1.5 %)
|
74 (4.8 %)
|
|
Gastrointestinal bleeding
|
199 (2.8 %)
|
140 (3.1 %)
|
28 (2.8 %)
|
31 (2.0 %)
|
|
Neurological symptoms
|
1379 (19.3 %)
|
1138 (24.9 %)
|
78 (7.8 %)
|
163 (10.5 %)
|
|
Nonthoracic pain
|
1217 (17.1 %)
|
682 (14.9 %)
|
103 (10.3 %)
|
432 (27.8 %)
|
|
Respiratory symptoms
|
948 (13.3 %)
|
526 (11.5 %)
|
220 (22.0 %)
|
202 (13.0 %)
|
|
Thoracic pain
|
1038 (14.6 %)
|
690 (15.1 %)
|
153 (15.3 %)
|
195 (12.6 %)
|
|
Worsening of general condition
|
837 (11.7 %)
|
258 (5.6 %)
|
308 (30.8 %)
|
271 (17.5 %)
|
|
Other symptom
|
676 (9.5 %)
|
603 (13.2 %)
|
0 (0.0 %)
|
73 (4.7 %)
|
|
Main diagnosis, n (%)
|
|
Cancer
|
297 (4.2 %)
|
234 (5.1 %)
|
29 (2.9 %)
|
34 (2.2 %)
|
|
Cardiovascular
|
1732 (24.3 %)
|
1003 (21.9 %)
|
413 (41.3 %)
|
316 (20.3 %)
|
|
Gastrointestinal
|
896 (12.6 %)
|
503 (11.0 %)
|
92 (9.2 %)
|
301 (19.4 %)
|
|
Infection
|
896 (12.6 %)
|
657 (14.3 %)
|
49 (4.9 %)
|
190 (12.2 %)
|
|
Metabolic
|
238 (3.3 %)
|
62 (1.4 %)
|
56 (5.6 %)
|
120 (7.7 %)
|
|
Neurological
|
1569 (22.0 %)
|
1150 (25.1 %)
|
160 (16.0 %)
|
259 (16.7 %)
|
|
Pulmonary
|
471 (6.6 %)
|
169 (3.7 %)
|
158 (15.8 %)
|
144 (9.3 %)
|
|
Other
|
1033 (14.5 %)
|
801 (17.5 %)
|
43 (4.3 %)
|
189 (12.2 %)
|
|
Comorbidities, n (%)
|
|
Cancer
|
968 (13.6 %)
|
678 (14.8 %)
|
79 (7.9 %)
|
211 (13.6 %)
|
|
Chronic renal failure
|
872 (12.2 %)
|
694 (15.2 %)
|
78 (7.8 %)
|
100 (6.4 %)
|
|
Congestive heart failure
|
487 (6.8 %)
|
286 (6.2 %)
|
118 (11.8 %)
|
83 (5.3 %)
|
|
COPD
|
359 (5.0 %)
|
229 (5.0 %)
|
51 (5.1 %)
|
79 (5.1 %)
|
|
Coronary heart disease
|
838 (11.7 %)
|
557 (12.2 %)
|
107 (10.7 %)
|
174 (11.2 %)
|
|
Dementia
|
223 (3.1 %)
|
147 (3.2 %)
|
67 (6.7 %)
|
9 (0.6 %)
|
|
Diabetes
|
1088 (15.3 %)
|
681 (14.9 %)
|
224 (22.4 %)
|
183 (11.8 %)
|
|
History of stroke
|
566 (7.9 %)
|
456 (10.0 %)
|
5 (0.5 %)
|
105 (6.8 %)
|
|
Hypertension
|
2795 (39.2 %)
|
1920 (41.9 %)
|
479 (47.9 %)
|
396 (25.5 %)
|
|
Substance abuse
|
460 (6.4 %)
|
303 (6.6 %)
|
52 (5.2 %)
|
105 (6.8 %)
|
|
Initial blood biomarkers, median (IQR)
|
|
Copeptin, (pmol/L)
|
10.74 (4.54, 38.90)
|
11.60 (4.70, 43.80)
|
15.02 (5.70, 59.42)
|
7.63 (3.95, 19.21)
|
|
Creatinine (micromol/L)
|
81.0 (67.0, 103.0)
|
85.0 (70.0, 106.0)
|
79.6 (70.7, 106.1)
|
67.0 (55.0, 84.0)
|
|
Glucose (mmol/L)
|
6.1 (5.3, 7.5)
|
6.2 (5.4, 7.5)
|
6.3 (5.3, 8.2)
|
5.8 (5.2, 6.9)
|
|
Hemoglobin (G/L)
|
13.6 (12.1, 14.8)
|
13.7 (12.2, 14.9)
|
12.9 (11.4, 14.4)
|
13.7 (12.4, 14.8)
|
|
PCT (ug/L)
|
0.08 (0.06, 0.13)
|
0.08 (0.06, 0.13)
|
0.09 (0.06, 0.15)
|
0.08 (0.06, 0.13)
|
|
ProADM (nmol/L)
|
0.79 (0.57, 1.24)
|
0.81 (0.60, 1.27)
|
0.98 (0.70, 1.62)
|
0.59 (0.45, 0.88)
|
|
Sodium (mmol/L)
|
139 (137, 140)
|
139 (137, 141)
|
138 (136, 140)
|
138 (137, 140)
|
|
WBC (G/L)
|
8.4 (6.6, 10.9)
|
8.5 (6.7, 11.0)
|
8.3 (6.4, 11)
|
8.1 (6.3, 10.8)
|
|
Initial triage score, n (%)
|
|
No emergency
|
774 (11.1 %)
|
638 (14.2 %)
|
0 (0.0 %)
|
136 (9.1 %)
|
|
Within 90 minutes
|
1746 (25.1 %)
|
1030 (23.0 %)
|
61 (6.1 %)
|
655 (43.9 %)
|
|
Within 30 minutes
|
3030 (43.5 %)
|
1783 (39.8 %)
|
693 (69.3 %)
|
554 (37.2 %)
|
|
Within 10 minutes
|
1256 (18.0 %)
|
910 (20.3 %)
|
219 (21.9 %)
|
127 (8.5 %)
|
|
Immediate treatment needed
|
163 (2.3 %)
|
117 (2.6 %)
|
27 (2.7 %)
|
19 (1.3 %)
|
|
Patient outcomes, n (%)
|
|
Site of care, n (%)
|
|
Outpatient treatment
|
1555 (27.2 %)
|
637 (19.8 %)
|
0 (0.0 %)
|
918 (61.6 %)
|
|
Length of stay, mean (SD)
|
6.0 (6.1)
|
5.7 (5.1)
|
5.0 (5.3)
|
9.5 (9.5)
|
|
Location after hospital/ED discharge, n (%)
|
|
Home
|
5983 (83.9 %)
|
3796 (82.9 %)
|
723 (72.3 %)
|
1464 (94.3 %)
|
|
Other institution
|
504 (7.1 %)
|
435 (9.5 %)
|
61 (6.1 %)
|
8 (0.5 %)
|
|
Rehabilitation
|
320 (4.5 %)
|
207 (4.5 %)
|
50 (5.0 %)
|
63 (4.1 %)
|
|
Other
|
325 (4.6 %)
|
141 (3.1 %)
|
166 (16.6 %)
|
18 (1.2 %)
|
|
Outcomes within 30 days, n (%)
|
|
Intensive care unit admission
|
453 (6.4 %)
|
181 (4.0 %)
|
153 (15.3 %)
|
119 (7.7 %)
|
|
Inhospital mortality
|
188 (2.6 %)
|
136 (3.0 %)
|
21 (2.1 %)
|
31 (2.0 %)
|
|
30-day mortality
|
331 (4.6 %)
|
252 (5.5 %)
|
45 (4.5 %)
|
34 (2.2 %)
|
|
Unplanned hospital readmission
|
590 (8.3 %)
|
311 (6.8 %)
|
184 (18.4 %)
|
95 (6.1 %)
|
