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Table 1 Characteristics of study groups

From: Decreased serum concentrations of sphingosine-1-phosphate in sepsis

 

Controls

All patients

Group A

Group B

Group C

**Significance (P) – Group A to C

SIRS + Infection

Severe sepsis

Septic shock

Number

214

100

40

30

30

N/A

*Age, years

36 (27–51)

59 (51–70)

59 (46–67)

60 (53–72)

65 (56–74)

n.s.

Men/Women, n (%)

129/85 (60/40)

58/42 (58/42)

22/18 (55/45)

20/10 (67/33)

16/14 (53/47)

n.s.

Admission medical/surgical, n (%)

N/A

56/44 (56/44)

20/20 (50/50)

20/10 (67/33)

16/14 (53/47)

n.s.

*SAPS II, median (IQR)

N/A

33 (24–42)

28 (17–35)

34 (30–41)

42 (30–47)

<0.01

*Length of ICU stay, days

N/A

7 (2–11)

2 (1–6)

8 (4–12)

11 (7–21)

<0.01

Death on ICU, n (%)

N/A

15 (15.0)

1 (2.5)

7 (23.3)

7 (23.3)

<0.05

  1. SIRS systemic inflammatory response syndrome, N/A not applicable, n.s. non-significant, SAPS II Simplified Acute Physiology Score II, IQR interquartile range, ICU intensive care unit
  2. *Data are presented as median and IQR
  3. **Groups were compared by using analysis-of-variance Kruskal-Wallis test