From: Decreased serum concentrations of sphingosine-1-phosphate in sepsis
 | Controls | All patients | Group A | Group B | Group C | **Significance (P) – Group A to C |
---|---|---|---|---|---|---|
SIRS + Infection | Severe sepsis | Septic shock | ||||
Number | 214 | 100 | 40 | 30 | 30 | N/A |
*Age, years | 36 (27–51) | 59 (51–70) | 59 (46–67) | 60 (53–72) | 65 (56–74) | n.s. |
Men/Women, n (%) | 129/85 (60/40) | 58/42 (58/42) | 22/18 (55/45) | 20/10 (67/33) | 16/14 (53/47) | n.s. |
Admission medical/surgical, n (%) | N/A | 56/44 (56/44) | 20/20 (50/50) | 20/10 (67/33) | 16/14 (53/47) | n.s. |
*SAPS II, median (IQR) | N/A | 33 (24–42) | 28 (17–35) | 34 (30–41) | 42 (30–47) | <0.01 |
*Length of ICU stay, days | N/A | 7 (2–11) | 2 (1–6) | 8 (4–12) | 11 (7–21) | <0.01 |
Death on ICU, n (%) | N/A | 15 (15.0) | 1 (2.5) | 7 (23.3) | 7 (23.3) | <0.05 |