Skip to main content

Table 2 Baseline characteristics of the patients

From: The efficacy of recombinant human soluble thrombomodulin for obstetric disseminated intravascular coagulation: a retrospective study

 

rhTM group

Control group

P valuea

 

(n = 37)

(n = 29)

Age, years, mean (SD)

33.0 (4.8)

31.8 (5.1)

0.326

Nulliparous, n (%)

20 (54.1)

16(55.1)

1.000

Twin pregnancy, n (%)

4 (10.8)

2 (6.9)

0.668

Delivery method, n (%)

   

 Normal vaginal delivery

10 (27.0)

7 (24.1)

1.000

 Vacuum extraction/Forceps delivery

9 (24.3)

6 (20.7)

0.775

Cesarean section

18 (48.6)

16 (55.2)

0.628

Diagnosis, n (%)

   

 Severe postpartum hemorrhageb

31 (83.7)

19 (65.5)

0.147

 Placental abruptionb

16 (43.2)

12 (41.4)

1.000

 Preeclampsia/eclampsia/HELLP syndromeb

7 (18.9)

10 (34.5)

0.169

Total hemorrhage volume, mL mean (SD)

2164.5 (1193.3)

1795.8 (1212.3)

0.221

Laboratory parameters, mean (SD)

   

 White blood count, × 103/μL

16.75 (5.61)

16.63 (6.02)

0.937

 Hemoglobin, g/dL

7.11 (2,00)

8.59 (2.70)

0.013

 Platelet count, × 109/Lb

104.5 (51.9)

123.4 (71.8)

0.219

 D-dimer, μg/mLb

116.3 (165.9)

116.6 (244.5)

0.995

 Fibrinogen, mg/dLb

175.0 (94.4)

234.4 (138.4)

0.051

 PT-INRb

1.346 (0.491)

1.426 (0.706)

0.587

JAAM DIC score, median (IR)

4.0 (3.0–6.0)

5.0 (2.0–7.0)

0.937

Obstetric DIC score, median (IR)

11.0 (9.0–14.0)

10.0 (8.0–13.0)

0.296

Theraputic intervention, n (%)

   

 ICU admission

10 (27.0)

8 (27.6)

1.000

 Protease inhibitor

16 (43.2)

17 (58.6)

0.321

  1. Data are expressed as group mean (SD), median (interquartile range (IR)), or proportion (%). a P value between the two groups from analysis using Student’s t–test or Mann–Whitney U test for continuous variables as appropriate, and by chi-square or Fisher’s exact test for categorical variables. bThe seven independent variables used in propensity score calculation. rhTM recombinant human soluble thrombomodulin, HELLP hemolysis, elevated liver enzymes, and low platelets, PT–INR prothrombin time–international normalized ratio, JAAM Japanese Association for Acute Medicine, ICU intensive care unit