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Table 2 Baseline characteristics of the patients

From: The efficacy of recombinant human soluble thrombomodulin for obstetric disseminated intravascular coagulation: a retrospective study

  rhTM group Control group P valuea
  (n = 37) (n = 29)
Age, years, mean (SD) 33.0 (4.8) 31.8 (5.1) 0.326
Nulliparous, n (%) 20 (54.1) 16(55.1) 1.000
Twin pregnancy, n (%) 4 (10.8) 2 (6.9) 0.668
Delivery method, n (%)    
 Normal vaginal delivery 10 (27.0) 7 (24.1) 1.000
 Vacuum extraction/Forceps delivery 9 (24.3) 6 (20.7) 0.775
Cesarean section 18 (48.6) 16 (55.2) 0.628
Diagnosis, n (%)    
 Severe postpartum hemorrhageb 31 (83.7) 19 (65.5) 0.147
 Placental abruptionb 16 (43.2) 12 (41.4) 1.000
 Preeclampsia/eclampsia/HELLP syndromeb 7 (18.9) 10 (34.5) 0.169
Total hemorrhage volume, mL mean (SD) 2164.5 (1193.3) 1795.8 (1212.3) 0.221
Laboratory parameters, mean (SD)    
 White blood count, × 103/μL 16.75 (5.61) 16.63 (6.02) 0.937
 Hemoglobin, g/dL 7.11 (2,00) 8.59 (2.70) 0.013
 Platelet count, × 109/Lb 104.5 (51.9) 123.4 (71.8) 0.219
 D-dimer, μg/mLb 116.3 (165.9) 116.6 (244.5) 0.995
 Fibrinogen, mg/dLb 175.0 (94.4) 234.4 (138.4) 0.051
 PT-INRb 1.346 (0.491) 1.426 (0.706) 0.587
JAAM DIC score, median (IR) 4.0 (3.0–6.0) 5.0 (2.0–7.0) 0.937
Obstetric DIC score, median (IR) 11.0 (9.0–14.0) 10.0 (8.0–13.0) 0.296
Theraputic intervention, n (%)    
 ICU admission 10 (27.0) 8 (27.6) 1.000
 Protease inhibitor 16 (43.2) 17 (58.6) 0.321
  1. Data are expressed as group mean (SD), median (interquartile range (IR)), or proportion (%). a P value between the two groups from analysis using Student’s t–test or Mann–Whitney U test for continuous variables as appropriate, and by chi-square or Fisher’s exact test for categorical variables. bThe seven independent variables used in propensity score calculation. rhTM recombinant human soluble thrombomodulin, HELLP hemolysis, elevated liver enzymes, and low platelets, PT–INR prothrombin time–international normalized ratio, JAAM Japanese Association for Acute Medicine, ICU intensive care unit