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Table 1 Obstetric DIC score

From: The efficacy of recombinant human soluble thrombomodulin for obstetric disseminated intravascular coagulation: a retrospective study

  Score
1. Underlying diseases  
 a. Placental abruption  
  Stiffening of the uterus, death of the fetus 5
  Stiffening of the uterus, survival of the fetus 4
  Confirmatory diagnosis of placental abruption by ultrasonic tomographic findings and CTG findings 4
 b. Amniotic fluid embolism  
  Acute cor pulmonale 4
  Artificial ventilation 3
  Assisted respiration 2
  Oxygen flux alone 1
 c. DIC-type postpartum hemorrhage  
  In case the blood from the uterus has low coagulability 4
  Hemorrhage of >2000 mL (within 24 hours after the start of hemorrhage) 3
  Hemorrhage of 1000–2000 mL (within 24 hours after the start of hemorrhage) 1
 d. Eclampsia  
  Eclamptic attack 4
 e. Severe infection  
  Those with fever accompanied by shock, bacteremia, and endotoxemia 4
  Continued fever or remittent fever 1
 f. Other underlying diseases 1
2. Clinical symptoms  
 a. Acute renal failure  
  Anuria (<5 mL/hour) 4
  Oliguria (5–20 mL/hour) 3
 b. Acute respiratory failure (amniotic fluid embolism excluded)  
  Artificial ventilation or occational assisted respiration 4
  Oxygen flux alone I
 c. Organ failure  
  Heart (rales or foamy sputum, etc.) 4
  Liver (visible jaundice, etc.) 4
  Brain (clouding of consciousness, convulsion, etc.) 4
  Digestive tract (necrotic enteritis, etc.) 4
  Other severe organ failure 4
 d. Hemorrhage diathesis  
  Macroscopic hematuria and melena, purpura, etc. 4
 e. Shock symptoms  
  Pulse rate ≥100/minute 1
  Blood pressure ≤90 mm Hg (systolic) or reduction ≥40 % 1
  Cold sweat 1
  Pallor 1
3. Laboratory findings  
  Serum FDP ≥10 pg/mL 1
  Platelet counts ≤100 × 109/L 1
  Fibrinogen ≤150 mg/dL 1
  PT ≥15 seconds (≤50 %) or hepaplastin test ≤ 50 % 1
  Erythrocyte sedimentation rate of ≤4 mm/15 minutes or ≤15 mm/hour 1
  Bleeding time ≥5 minutes 1
  Other coagulation and fibrinolysis factors;  
  antithrombin ≤18 mg/dL or ≤60 %, plasminogen, prekallikrein, other factors of ≤50 % 1
Diagnosis  
8–12 points Suspected DIC
≥13 points Definite DIC
  1. DIC disseminated intravascular coagulation, CTG cardiotocography, FDP fibrin/fibrinogen degradation products, PT prothrombin time