Characteristics | AKI (n = 1172) | Survivors (n = 871) | Non-survivors (n = 301) | P value |
---|---|---|---|---|
Male sex | 742 (63.3) | 548 (62.9) | 194 (64.5) | 0.677 |
Age (yr) | 67 (54–78) | 64 (52–77) | 74 (60–82) | <0.001 |
ICU admission | Â | Â | Â | Â |
APACHE II score | 17 (12–23) | 15 (11–21) | 23 (17–29) | <0.001 |
SAPS II score | 40 (31–52) | 37 (28–47) | 52 (41–64) | <0.001 |
SOFA score | 7 (5–10) | 7 (4–10) | 9 (7–12) | <0.001 |
Vasoactive therapy | 576 (49.1) | 419 (48.1) | 157 (52.2) | 0.229 |
Mechanical ventilation | 818 (69.8) | 614 (70.5) | 204 (67.8) | 0.383 |
Baseline creatinine (μmol/L) | 84.9 (73.0–97.0) | 84.0 (72.1–97.0) | 86.9 (75.0–97.8) | 0.78 |
Sepsis | 512 (43.7) | 309 (35.5) | 203 (67.4) | <0.001 |
Comorbid diseases | Â | Â | Â | Â |
 Cancer | 164 (14.0) | 112 (12.9) | 52 (17.2) | 0.067 |
 Hypertension | 523 (44.6) | 379 (43.5) | 144 (47.8) | 0.202 |
 Cardiovascular | 274 (23.4) | 177 (20.3) | 97 (32.2) | <0.001 |
 Chronic kidney disease | 111 (9.5) | 79 (9.1) | 32 (10.6) | 0.493 |
  Diabetes | 240 (20.5) | 173 (19.9) | 67 (22.2) | 0.407 |
Category of ICU admission diagnosis | ||||
 Respiratory | 208 (17.7) | 125 (14.4) | 83 (27.6) | <0.001 |
 Neurologic | 178 (15.2) | 134 (15.4) | 44 (14.6) | 0.781 |
 Postsurgery | 556 (47.4) | 443 (50.8) | 113 (37.5) | <0.001 |
 Cardiovascular | 233 (19.9) | 170 (19.5) | 63 (20.9) | 0.615 |
ICU course | Â | Â | Â | Â |
 Cumulative fluid balance in 3 days (L) | 1.40 (−0.49 to 3.54) | 0.93 (−0.80 to 2.93) | 2.77 (0.86–5.01) | <0.001 |
 Oliguria | 96 (8.2) | 46 (5.3) | 50 (16.6) | <0.001 |
 Use of diuretics (%) | 872 (74.4) | 635 (72.9) | 237 (78.7) | 0.047 |
Outcomes | Â | Â | Â | Â |
 AKI stage |  |  |  |  |
 1 | 496 (42.3) | 424 (48.7) | 72 (23.9) |  |
 2 | 289 (24.7) | 215 (24.7) | 74 (24.6) | <0.001 |
 3 | 387 (33.0) | 232 (26.6) | 155 (51.5) |  |
 RRT | 222 (18.9) | 125 (14.4) | 97 (32.2) | <0.001 |
 Length of ICU stay (days) | 7 (5–14) | 7 (4–13) | 8 (6–14) | 0.001 |