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Table 4 Performance of multivariable models for predicting 28-day mortality in patients with early sepsis

From: Prognostic significance of the angiopoietin-2/angiopoietin-1 and angiopoietin-1/Tie-2 ratios for early sepsis in an emergency department

 

Variable

Cutoff

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

LR+

LR−

28-day mortality

Ang-2/Ang-1

1.94

79.7

81.3

78.4

82.5

3.98

0.31

 

Ang-1/Tie-2 (×103)

30.0

73.0

82.4

79.4

77.9

4.15

0.33

 

PCT

5.27

62.3

84.9

60.3

85.4

2.03

0.22

 

MEDS score

14.5

70.6

76.3

56.2

90.7

3.35

0.27

  1. Abbreviations: Ang angiopoietin, LR− negative likelihood ratio, LR+ positive likelihood ratio, MEDS Mortality in Emergency Department Sepsis, NPV negative predictive value, PCT procalcitonin, PPV positive predictive value, Tie-2 tyrosine kinase with immunoglobulin-like loop epidermal growth factor homology domain 2
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Critical Care

ISSN: 1364-8535