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Table 2 Multivariable analyses for the predictive value of PCT for death, adjusting for potential confounders

From: Procalcitonin and mortality in status epilepticus: an observational cohort study

 

Total cohort

Patients without SE of infectious etiology

 

HR

95 % CI

P value

HR

95 % CI

P value

Death

      

ᅟPCT at SE onset, per μg/L

1.44

1.11 − 1.87

0.007

1.40

1.09 − 1.82

0.010

ᅟAcute etiology of SE1

0.54

0.19 − 1.55

0.255

0.65

0.23 − 1.82

0.411

ᅟInfections during SE

3.04

1.20 − 7.71

0.019

3.45

1.32 − 9.00

0.011

ᅟCharlson comorbidity index, per unit

1.35

1.09 − 1.67

0.005

1.27

1.02 − 1.57

0.030

ᅟSTESS, per unit2

1.39

1.03 − 1.88

0.035

1.48

1.07 − 2.03

0.017

GOS 1 − 3

      

ᅟPCT at SE onset, per μg/L

1.29

1.02 − 1.62

0.032

1.29

1.03 − 1.61

0.027

ᅟAcute etiology of SE1

0.59

0.34 − 1.03

0.062

0.68

0.38 − 1.22

0.196

ᅟInfections during SE

1.67

0.98 − 2.85

0.059

1.68

0.97 − 2.94

0.066

ᅟCharlson comorbidity index, per unit

1.05

0.93 − 1.18

0.466

1.01

0.89 − 1.15

0.845

ᅟSTESS, per unit2

1.04

0.89 − 1.22

0.628

1.06

0.90 − 1.24

0.498

  1. 1Acute etiology was defined as brain tumors, intracranial hemorrhage, acute cerebral infarct (<1 week before SE), intoxication or drug withdrawal, traumatic brain injury (<1 week before SE), encephalitis, metabolic derangements, and brain surgery <1 week before SE according to the guidelines of the International League Against Epilepsy (ILAE) [52]. 2STESS = status epilepticus severity score, including age, level of consciousness, worst seizure type, and seizure history [3, 4]. HR hazard ratio, PCT procalcitonin, SE status epilepticus, GOS Glasgow outcome score; Bold p values are considered significant