Table 2 Glasgow Royal Infirmary (GRI) dataset patient characteristics and univariate analysis
Variable | All patients (n = 84) | ICU survivor (n = 59) | ICU death (n = 25) | P value |
|---|---|---|---|---|
Age mean (range) | 50.2 (29–80) | 49.7 (29–80) | 51.4 (32–72) | 0.55 |
Gender, male, n (%) | 59 (70.2 %) | 41 (69.5 %) | 18 (72.0 %) | 1.00 |
SIMD category | 0.44 | |||
1–2 (deprived), n (%) | 68 (81.0 %) | 46 (78.0 %) | 22 (88.0 %) | |
3–5 (non-deprived), n (%) | 16 (19.0 %) | 13 (22.0 %) | 3 (12.0 %) | |
Alcoholic aetiology, n (%) | 70 (83.3 %) | 48 (81.3 %) | 22 (88.0 %) | 0.54 |
Encephalopathy, any, n (%) | 29 (34.5 %) | 19 (32.2 %) | 10 (40.0 %) | 0.66 |
Ascites, any, n (%) | 35 (41.7 %) | 22 (37.3 %) | 13 (52.0 %) | 0.31 |
Sodium, mmol/L, mean (range) | 136.4 (113.0–151.0) | 136.7 (113.0–151.0) | 135.7 (128.0–147.0) | 0.52 |
Potassium, mmol/L, mean (range) | 4.1 (2.6–7.0) | 4.0 (2.6–7.0) | 4.3 (2.9–5.9) | 0.27 |
Urea, μmol/L, median (IQR) | 8.1 (4.1–12.7) | 7.7 (4.4–12.1) | 9.2 (4.0–14.5) | 0.44 |
Lactate, mmol/L, median (IQR) | 1.9 (1.3–2.7) | 1.7 (1.2–2.2) | 4.1 (2.0–8.0) | <0.001 |
Creatinine, μmol/L, median (IQR) | 81.5 (57.8–158.8) | 75.0 (57.5–138.5) | 144.0 (69.0–199.0 ) | 0.056 |
WCC, × 109/L, mean (range) | 13.6 (0.8–41.7) | 13.6 (0.8–36.4) | 13.6 (1.5–41.7) | 0.99 |
Bilirubin, μmol/L, median (IQR) | 45.5 (22.3–106.8) | 33.0 (18.0–76.5) | 71.0 (40.0–182.0) | 0.0048 |
PT ratio, median (IQR) | 1.5 (1.2–2.0) | 1.5 (1.2–1.8) | 1.8 (1.5–2.5) | 0.012 |
Albumin, g/L, mean (range) | 21.8 (8.0–79.0) | 22.6 (8.0–79.0) | 19.8 (10.0–33.0) | 0.14 |
Platelets, × 109/L, mean (range) | 138.5 (6.0–487.0) | 145.4 (25.0–487.0) | 122.2 (6.0–371.0) | 0.31 |
PaO2, kPa, median (IQR) | 12.4 (9.9–18.1) | 12.5 (9.8–19.2) | 12.1 (10.0–15.8) | 0.65 |
PaO2/FiO2 ratio, median (IQR) | 21.8 (12.8–35.6) | 24.5 (14.8–38.6) | 15.8 (11.7–25.3) | 0.032 |
APACHE II, mean (range) | 23.5 (2.0–47.0) | 21.5 (2.0–39.0) | 28.3 (14.0–47.0) | <0.001 |
SOFA, mean (range) | 9.7 (3.0–20.0) | 8.6 (3.0–15.0) | 12.3 (4.0–20.0) | <0.001 |
MELD, median (IQR) | 19.0 (13.3–25.0) | 16.0 (12.0–21.0) | 25.0 (20.0–30.0) | <0.001 |
UKELD, median (IQR) | 52.0 (47.3–58.0) | 51.0 (47.0–53.0) | 58 (50.0–61.0) | 0.0016 |
CTP, median (IQR) | 9.0 (7.3–11.0) | 9.0 (7.0–11.0) | 11.0 (9.0–13.0) | 0.012 |
CTP + L, median (IQR) | 11.0 (9.0–14.3) | 10.0 (9.0–12.5) | 15.0 (13.0–19.0) | <0.001 |
CLIF-SOFA, median (IQR) | 10.0 (7.0–12.3) | 9.0 (6.0–11.0) | 12.0 (10.0–14.0) | <0.001 |
RFH, median (IQR) | 0.41 (–0.93–2.00) | −0.52 (−1.64–0.73) | 2.12 (0.52–3.14) | <0.001 |