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Table 2 Glasgow Royal Infirmary (GRI) dataset patient characteristics and univariate analysis

From: Validation and analysis of prognostic scoring systems for critically ill patients with cirrhosis admitted to ICU

Variable All patients (n = 84) ICU survivor (n = 59) ICU death (n = 25) P value
Age mean (range) 50.2 (29–80) 49.7 (29–80) 51.4 (32–72) 0.55
Gender, male, n (%) 59 (70.2 %) 41 (69.5 %) 18 (72.0 %) 1.00
SIMD category     0.44
 1–2 (deprived), n (%) 68 (81.0 %) 46 (78.0 %) 22 (88.0 %)  
 3–5 (non-deprived), n (%) 16 (19.0 %) 13 (22.0 %) 3 (12.0 %)  
Alcoholic aetiology, n (%) 70 (83.3 %) 48 (81.3 %) 22 (88.0 %) 0.54
Encephalopathy, any, n (%) 29 (34.5 %) 19 (32.2 %) 10 (40.0 %) 0.66
Ascites, any, n (%) 35 (41.7 %) 22 (37.3 %) 13 (52.0 %) 0.31
Sodium, mmol/L, mean (range) 136.4 (113.0–151.0) 136.7 (113.0–151.0) 135.7 (128.0–147.0) 0.52
Potassium, mmol/L, mean (range) 4.1 (2.6–7.0) 4.0 (2.6–7.0) 4.3 (2.9–5.9) 0.27
Urea, μmol/L, median (IQR) 8.1 (4.1–12.7) 7.7 (4.4–12.1) 9.2 (4.0–14.5) 0.44
Lactate, mmol/L, median (IQR) 1.9 (1.3–2.7) 1.7 (1.2–2.2) 4.1 (2.0–8.0) <0.001
Creatinine, μmol/L, median (IQR) 81.5 (57.8–158.8) 75.0 (57.5–138.5) 144.0 (69.0–199.0 ) 0.056
WCC, × 109/L, mean (range) 13.6 (0.8–41.7) 13.6 (0.8–36.4) 13.6 (1.5–41.7) 0.99
Bilirubin, μmol/L, median (IQR) 45.5 (22.3–106.8) 33.0 (18.0–76.5) 71.0 (40.0–182.0) 0.0048
PT ratio, median (IQR) 1.5 (1.2–2.0) 1.5 (1.2–1.8) 1.8 (1.5–2.5) 0.012
Albumin, g/L, mean (range) 21.8 (8.0–79.0) 22.6 (8.0–79.0) 19.8 (10.0–33.0) 0.14
Platelets, × 109/L, mean (range) 138.5 (6.0–487.0) 145.4 (25.0–487.0) 122.2 (6.0–371.0) 0.31
PaO2, kPa, median (IQR) 12.4 (9.9–18.1) 12.5 (9.8–19.2) 12.1 (10.0–15.8) 0.65
PaO2/FiO2 ratio, median (IQR) 21.8 (12.8–35.6) 24.5 (14.8–38.6) 15.8 (11.7–25.3) 0.032
APACHE II, mean (range) 23.5 (2.0–47.0) 21.5 (2.0–39.0) 28.3 (14.0–47.0) <0.001
SOFA, mean (range) 9.7 (3.0–20.0) 8.6 (3.0–15.0) 12.3 (4.0–20.0) <0.001
MELD, median (IQR) 19.0 (13.3–25.0) 16.0 (12.0–21.0) 25.0 (20.0–30.0) <0.001
UKELD, median (IQR) 52.0 (47.3–58.0) 51.0 (47.0–53.0) 58 (50.0–61.0) 0.0016
CTP, median (IQR) 9.0 (7.3–11.0) 9.0 (7.0–11.0) 11.0 (9.0–13.0) 0.012
CTP + L, median (IQR) 11.0 (9.0–14.3) 10.0 (9.0–12.5) 15.0 (13.0–19.0) <0.001
CLIF-SOFA, median (IQR) 10.0 (7.0–12.3) 9.0 (6.0–11.0) 12.0 (10.0–14.0) <0.001
RFH, median (IQR) 0.41 (–0.93–2.00) −0.52 (−1.64–0.73) 2.12 (0.52–3.14) <0.001
  1. SIMD Scottish Index of Multiple Deprivation, WCC white cell count, PT prothrombin time, PaO2, arterial partial pressure of oxygen, FiO2, inspired oxygen fraction, APACHE II acute physiology and chronic health evaluation II, SOFA sequential organ failure assessment, MELD model of end-stage liver disease, UKELD United Kingdom model for end-stage liver disease, CTP Child-Turcotte Pugh, CTP + L Child-Turcotte Pugh + lactate, CLIF-SOFA chronic liver failure sequential organ failure assessment, RFH Royal Free Hospital score