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Table 4 Acid–base status at start of RCA-CVVHD treatment and end of observation

From: Safety and efficacy of regional citrate anticoagulation in continuous venovenous hemodialysis in the presence of liver failure: the Liver Citrate Anticoagulation Threshold (L-CAT) observational study

 

Normal liver function (bilirubin ≤2 mg/dl)

Mild liver failure (bilirubin 2–7 mg/dl)

Severe liver failure (bilirubin ≥7 mg/dl)

Start

End

Start

End

Start

End

Arterial pH

7.33 ± 0.10

7.41 ± 0.06

7.33 ± 0.10

7.44 ± 0.05

7.35 ± 0.10

7.42 ± 0.05

Arterial serum bicarbonate (mmol/L)

20.9 ± 4.8

25.2 ± 2.4

20.5 ± 5.2

25.8 ± 2.0

20.8 ± 4.3

24.7 ± 2.7

Base excess (mmol/L)

−4.1 ± 5.8

1.3 ± 3.2

−4.6 ± 6.3

1.4 ± 6.8

−3.9 ± 5.0

−0.9 ± 6.8

Arterial lactate (mmol/L)

2.27 ± 3.61

1.71 ± 2.22

3.78 ± 4.53

2.63 ± 3.25

2.81 ± 2.69

3.41 ± 4.93

Arterial pO2 (mmHg)

101 ± 34

96 ± 29

99 ± 31

92 ± 28

93 ± 27

96 ± 21

Arterial pCO2 (mmHg)

40 ± 11

41 ± 9

41 ± 11

43 ± 8

39 ± 11

39 ± 7

  1. pCO2 carbon dioxide pressure, pO2 oxygen pressure, RCA-CVVHD regional citrate anticoagulation and continuous venovenous hemodialysis
  2. Mean ± standard deviation