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Table 3 RCA-CVVHD flows and citrate dose at start of treatment and end of observation

From: Safety and efficacy of regional citrate anticoagulation in continuous venovenous hemodialysis in the presence of liver failure: the Liver Citrate Anticoagulation Threshold (L-CAT) observational study

 

Normal liver function (bilirubin ≤2 mg/dl)

Mild liver failure (bilirubin 2–7 mg/dl)

Severe liver failure (bilirubin ≥7 mg/dl)

Start

End

Start

End

Start

End

Blood flow (ml/min)

109 ± 24

114 ± 25

109 ± 25

117 ± 28

110 ± 24

107 ± 20

Dialysate flow (ml/h)

2144 ± 502

2292 ± 500

2128 ± 405

2328 ± 567

2098 ± 403

2319 ± 501

Net ultrafiltration (ml/h)

77 ± 108

74 ± 114

68 ± 100

84 ± 105

84 ± 103

85 ± 102

Citrate dose (mmol/L blood)

4.0 ± 0.1

3.8 ± 0.2

4.0 ± 0.1

3.9 ± 0.3

4.0 ± 0.1

4.1 ± 0.4

  1. RCA-CVVHD regional citrate anticoagulation and continuous venovenous hemodialysis
  2. Mean ± SD. For dialysate to blood flow ratio and calcium dose, see Figs. 2 and 3, respectively