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Table 4 Impact of renal protection fluid therapy on outcome

From: Relationship between a perioperative intravenous fluid administration strategy and acute kidney injury following off-pump coronary artery bypass surgery: an observational study

  Unadjusted Multivariable adjusted IPTW adjusted
  β (95 % CI) P value β (95 % CI) P value β (95 % CI) P value
Extubation time (h) −0.28 (−0.37, −0.18) <0.001 −0.28 (−0.37, −0.19) <0.001 −0.33 (−0.42, −0.23) <0.001
Intensive care unit stay (h) 0.02 (−0.06, 0.09) 0.682 0.03 (−0.04, 0.10) 0.400 −0.06 (−0.13, 0.02) 0.159
Hospital stay (d) −0.11 (−0.17, −0.04) 0.001 −0.11 (−0.17, −0.05) <0.001 −0.18 (−0.24, −0.11) <0.001
  OR (95 % CI) P value OR (95 % CI) P value OR (95 % CI) P value
Acute kidney injury by KDIGO 0.28 (0.18–0.41) <0.001 0.31 (0.19–0.50) <0.001 0.23 (0.15–0.35) <0.001
KDIGO stage ≥2 0.28 (0.13–0.60) 0.001 0.30 (0.12–0.75) 0.009 0.12 (0.04–0.36) <0.001
Renal replacement therapy 0.40 (0.09–1.79) 0.230
Persistent acute kidney injury 0.16 (0.06–0.45) <0.001 0.20 (0.06–0.67) 0.008 0.20 (0.08–0.52) 0.001
In-hospital death 0.34 (0.04–2.80) 0.318
  1. IPTW inverse probability of treatment weighting, CI confidence interval, OR odds ratio, KDIGO Kidney Disease: Improving Global Outcomes classification