Relationship between a perioperative intravenous fluid administration strategy and acute kidney injury following off-pump coronary artery bypass surgery: an observational study

Table 3 Postoperative outcomes in the study groups

	Control group	RPF group	P value
Number of patients	554	229
Acute kidney injury
RIFLE	212 (38.3)	33 (14.4)	<0.001
AKIN	168 (30.3)	24 (10.5)	<0.001
KDIGO	210 (37.9)	33 (14.4)	<0.001
KDIGO stage ≥2	63 (11.4)	8 (3.5)	<0.001
Renal replacement therapy	12 (2.2)	2 (0.9)	0.345
Persistent acute kidney injury	59 (10.7)	4 (1.7)	<0.001
Extubation time (h)	10.5 [7.5–16.0]	7.5 [5.5–12.3]	<0.001
Intensive care unit stay (h)	47.0 [39.8–50.5]	47.0 [42.5–49.0]	0.695
Maximal SOFA-C score	3.0 [2.0–3.0]	3.0 [0–3.0]	0.181
Hospital stay (days)	8.0 [7.0–10.0]	7.0 [7.0–9.0]	<0.001
In-hospital deaths	7 (1.3)	1 (0.4)	0.512

RPF renal protective fluid management, RIFLE risk, injury, failure, loss, and end-stage kidney disease classification, AKIN Acute Kidney Injury Network classification, KDIGO Kidney Disease Improving Global Outcomes classification, SOFA-C cardiovascular sequential organ failure assessment in the first 24 h
Data are expressed as number of patients (%) or median [interquartile range]

ISSN: 1364-8535