Skip to main content

Table 4 Clinical outcomes by definition of severe sepsis

From: Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

Outcome

Physician diagnosis

Both criteria

Consensus criteria

p value*

Vasoactive-free days, median (IQR)

27 (22–28)

22 (6–26)

26 (17–28)

<0.001

Ventilator-free days, median (IQR)

19 (2–27)

16 (0–24)

18 (0–26)

0.07

NPMODSa

47 (34)

131 (44)

97 (36)

0.10

PICU mortality

23 (17)

82 (27)

57 (21)

0.042

At least mild disabilityb

24 (22)

67 (31)

50 (24)

0.15

At least moderate disabilityc

14 (13)

36 (17)

37 (18)

0.46

  1. Data presented as n (%) unless otherwise noted
  2. IQR interquartile range, NPMODS new or progressive multiorgan dysfunction syndrome, PICU pediatric intensive care unit
  3. *Statistical comparisons using Kruskal-Wallis or Fisher’s exact test
  4. aNPMODS considered starting the day after sepsis recognition
  5. bAny increase in Pediatric Overall Performance Category from baseline to hospital discharge in the 534 hospital survivors
  6. cDischarge Pediatric Overall Performance Category ≥3 and an increase of at least 1 from baseline in the 534 hospital survivors
Back to article page