|
Outcome
|
Physician diagnosis
|
Both criteria
|
Consensus criteria
|
p value*
|
|---|
|
Vasoactive-free days, median (IQR)
|
27 (22–28)
|
22 (6–26)
|
26 (17–28)
|
<0.001
|
|
Ventilator-free days, median (IQR)
|
19 (2–27)
|
16 (0–24)
|
18 (0–26)
|
0.07
|
|
NPMODSa
|
47 (34)
|
131 (44)
|
97 (36)
|
0.10
|
|
PICU mortality
|
23 (17)
|
82 (27)
|
57 (21)
|
0.042
|
|
At least mild disabilityb
|
24 (22)
|
67 (31)
|
50 (24)
|
0.15
|
|
At least moderate disabilityc
|
14 (13)
|
36 (17)
|
37 (18)
|
0.46
|
- Data presented as n (%) unless otherwise noted
-
IQR interquartile range, NPMODS new or progressive multiorgan dysfunction syndrome, PICU pediatric intensive care unit
- *Statistical comparisons using Kruskal-Wallis or Fisher’s exact test
-
aNPMODS considered starting the day after sepsis recognition
-
bAny increase in Pediatric Overall Performance Category from baseline to hospital discharge in the 534 hospital survivors
-
cDischarge Pediatric Overall Performance Category ≥3 and an increase of at least 1 from baseline in the 534 hospital survivors
