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Table 5 Most frequent patterns of antibiotic treatment

From: Improvement of antibiotic therapy and ICU survival in severe non-pneumococcal community-acquired pneumonia: a matched case–control study

Variable

All patients

CAPUCI I group

CAPUCI II group

p value

(n = 144)

(n = 72)

(n = 72)

 

Cephalosporin and macrolide

58 (40.1)

35 (48.5)

23 (32.0)

0.06

 Ceftriaxone/cefotaxime and clarithromycin

29 (20.1)

27 (37.5)

2 (2.8)

<0.01

 Ceftriaxone/cefotaxime and azithromycin

18 (12.4)

0 (0)

18 (25.0)

<0.01

 Other cephalosporin and macrolide

11 (7.6)

8 (11.1)

3 (4.2)

0.21

Cephalosporin and quinolone

31 (21.5)

6 (8.4)

25 (34.6)

<0.01

 Cefotaxime/ceftriaxone and levofloxacin

25 (17.3)

4 (5.6)

21 (29.0)

<0.01

 Other cephalosporin and quinolone

6 (4.2)

2 (2.8)

4 (5.6)

0.68

Penicillin and macrolide

9 (6.3)

2 (2.8)

7 (9.7)

0.17

 Piperacillin-tazobactam and azithromycin

5 (3.5)

0 (0)

5 (6.9)

0.06

 Other penicillin and macrolide

4 (2.8)

2 (2.8)

2 (2.8)

1.00

Amoxicillin-clavulanate

8 (5.6)

8 (11.1)

0 (0)

<0.01

Ceftriaxone/cefotaxime

7 (4.9)

5 (6.9)

2 (2.8)

0.44

Levofloxacin

6 (4.2)

4 (5.6)

2 (2.8)

0.68

Miscellaneous combined therapy

22 (15.3)

12 (16.7)

10 (13.9)

0.78

Miscellaneous monotherapy

3 (2.1)

0 (0)

3 (4.2)

0.25

Overall

144 (100)

72 (100)

72 (100)

 
  1. Data are presented as n (%). Significant p values are indicated in bold. p value calculated between CAPUCI I and CAPUCI II groups