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Table 2 Baseline and resuscitation data according to age, sex, and treatment

From: Estrogen administered after cardiac arrest and cardiopulmonary resuscitation ameliorates acute kidney injury in a sex- and age-specific manner

Group

Treatment

Numbera

Age, week

Body weight, g

Epinephrine dose, μg/g body weight

Epinephrine dose, g

CPR time, s

Survival rate, %

Young male

VEH

15

11.1 (0.4)

25.0 (1.6)

0.53 (0.09)

13.2 (2.0)

129 (29)

68

EST

15

11.2 (0.4)

25.1 (1.8)

0.51 (0.11)

12.7 (2.2)

118 (37)

68

P *

 

0.90

0.97

0.09

0.71

0.42

1

Young female

VEH

14

12.5 (2.0)

19.7 (0.8)

0.75 (0.08)

14.8 (1.6)

158 (28)

64

EST

14

12.9 (1.7)

19.9 (1.1)

0.71 (0.11)

14.0 (1.9)

151 (33)

88

P *

 

0.58

0.94

0.99

0.42

0.75

0.10

Aged male

VEH

8

83.8 (2.9)

34.9 (6.8)

0.42 (0.10)

14.3 (1.9)

136 (36)

71

EST

10

82.6 (3.1)

39.2 (8.6)

0.36 (0.09)

13.6 (1.5)

138 (27)

67

P *

 

0.26

0.26

0.11

0.33

0.87

0.60

Aged female

VEH

9

81.4 (2.4)

29.1 (5.1)

0.51 (0.13)

14.2 (1.9)

142 (35)

100

EST

10

82.2 (1.4)

31.1 (4.3)

0.42 (0.09)

12.9 (2.1)

130 (35)

83

P *

 

0.38

0.33

0.11

0.16

0.44

0.49

  1. Data are presented as mean (standard deviation)
  2. CPR Cardiopulmonary resuscitation, VEH vehicle, EST 17β-estradiol
  3. anumber of survives
  4. *P values shown for Sidak’s multiple comparison test or chi-squared test when appropriate
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Critical Care

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