Variable | All patients | Intervention | Control | p value |
---|---|---|---|---|
(n = 88) | (n = 44) | (n = 44) | ||
Male gender | 54 (61.4) | 29 (65.9) | 25 (56.8) | 0.381 |
Age, years | 51.2 ± 19.6 | 50.4 ± 18.5 | 52.0 ± 20.8 | 0.697 |
Admission category | 0.373 | |||
Medical | 30 (34.1) | 13 (29.5) | 17 (38.6) | |
Elective surgery | 1 (1.1) | 0 | 1 (2.3) | |
Emergency surgery | 57 (64.8) | 31 (70.5) | 26 (59.1) | |
ICU cause of admission | 0.822 | |||
Polytrauma | 21 (23.9) | 12 (27.3) | 9 (20.5) | |
Sepsis | 20 (22.7) | 10 (22.7) | 10 (22.7) | |
Intracranial hemorrhage | 14 (15.9) | 7 (15.9) | 7 (15.9) | |
TBI | 11 (12.5) | 6 (13.6) | 5 (11.4) | |
Respiratory failure | 5 (5.7) | 3 (6.8) | 2 (4.5) | |
Other | 17 (19.3) | 6 (13.6) | 11 (25.0) | |
Sepsis at enrollment | 47 (53.4) | 22 (50.0) | 25 (56.7) | |
Severe sepsis | 14 (15.9) | 4 (9.1) | 10 (22.7) | 0.103 |
Septic shock | 33 (37.5) | 18 (40.9) | 15 (34.0) | |
Comorbidities | ||||
Hypertension | 32 (36.4) | 16 (36.4) | 16 (36.4) | 1.000 |
Diabetes mellitus | 16 (18.2) | 7 (15.9) | 9 (20.5) | 0.580 |
Stroke | 8 (9.1) | 4 (9.1) | 4 (9.1) | 1.000 |
Cancer | 7 (8.0) | 4 (9.1) | 3 (6.8) | 0.694 |
COPD | 4 (4.5) | 1 (2.3) | 3 (6.8) | 0.306 |
APACHE II, points | 19.5 (15.0–22.0) | 20.0 (16.0–24.0) | 17.5 (14.0–22.0) | 0.075 |
SOFA at enrollment, points | 7.5 (6; 10) | 9 (6–11) | 7 (6–9) | 0.294 |
TISS-28 at enrollment | 37.5 (32.2–41.7) | 36.0 (33.0–40.5) | 38.0 (31.0–42.0) | 0.738 |
Lactate at enrollment, mmol/l | 1.7 (1.3–2.1) | 1.6 (1.2–2.1) | 1.7 (1.3–2.1) | 0.512 |
Time to ICU admission, days | 1.0 (0.7–3.0) | 1.0 (0–3.0) | 2.0 (1.0–4.0) | 0.388 |
Time to enrollment, hours | 50.5 (32.0–66.0) | 46.0 (33.0–66.0) | 51.0 (30.0–67.0) | 0.897 |