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Table 3 Administrative and clinical outcomes by fluid cohort

From: Impact of intravenous fluid composition on outcomes in patients with systemic inflammatory response syndrome

Outcome/Complication Saline Balanced Unadjusted odds ratio (95 % confidence interval) Adjusted odds ratio (95 % confidence interval)
(n = 1558) % (n) (n = 1558) % (n)
Administrative outcomes
 Cardiac 8.66 (135) 4.43 (69) 0.488 (0.362–0.659) 0.51 (0.378–0.689)
 Hemorrhage 0.71 (11) 0.51 (8) 0.726 (0.291–1.809) 0.781 (0.311–1.961)
 Infectious 10.14 (158) 6.03 (94) 0.569 (0.436–0.742) 0.618 (0.471–0.809)
 Gastrointestinal 5.46 (85) 5.13 (80) 0.938 (0.685–1.284) 0.969 (0.707–1.328)
 Neurologic 1.16 (18) 0.83 (13) 0.72 (0.352–1.474) 0.817 (0.395–1.69)
 Acute renal failure 4.36 (68) 3.34 (52) 0.757 (0.524–1.093) 0.917 (0.625–1.344)
 Respiratory failure 5.46 (85) 3.47 (54) 0.622 (0.439–0.882) 0.692 (0.485–0.986)
 New organ failure 9.11 (142) 7.12 (111) 0.765 (0.59–0.991) 0.872 (0.667–1.141)
Clinical outcomes
 Hospital mortality 3.27 (51) 1.03 (16) 0.307 (0.174–0.54) 0.378 (0.211–0.676)
 30-day readmissions 9.5 (148) 7.64 (119) 0.788 (0.612–1.014) 0.802 (0.622–1.032)
 60-day readmissions 13.54 (211) 10.91 (170) 0.782 (0.63–0.97) 0.798 (0.643–0.991)
 90-day readmissions 16.56 (258) 12.58 (196) 0.725 (0.593–0.886) 0.741 (0.606–0.907)
Cardiac
 Dysrhythmia 10.65 (166) 6.87 (107) 0.618 (0.48–0.797) 0.649 (0.502–0.838)
 Cardiac stress 6.42 (100) 2.05 (32) 0.306 (0.204–0.458) 0.341 (0.226–0.515)
 Heart failure 4.04 (63) 1.48 (23) 0.356 (0.219–0.576) 0.401 (0.246–0.653)
Hemorrhage/Hematologic
 Coagulopathya 11.09 (150) 7.71 (106) 0.67 (0.516–0.87) 0.717 (0.55–0.934)
 Received blood transfusion 2.92 (46) 2.27 (36) 0.777 (0.5–1.209) 0.851 (0.544–1.33)
 Bleeding 20.09 (313) 19.96 (311) 0.992 (0.832–1.182) 1.074 (0.897–1.286)
Infectious     
 Pneumonia 6.03 (94) 2.12 (33) 0.337 (0.225–0.504) 0.393 (0.259–0.596)
 Sepsis 10.53 (164) 5.65 (88) 0.509 (0.389–0.666) 0.568 (0.431–0.75)
 Urinary tract infection 5.91 (92) 4.69 (73) 0.783 (0.571–1.074) 0.904 (0.653–1.252)
 Line infection 0.77 (12) 0 - -
Gastrointestinal
 Cholecystitis 4.75 (74) 3.53 (55) 0.734 (0.514–1.048) 0.836 (0.58–1.203)
Renal
 Acute kidney injury 5.46 (85) 4.43 (69) 0.803 (0.580–1.112) 0.920 (0.658–1.286)
Electrolyte abnormalities
 Low magnesium with replacement 4.36 (68) 2.12 (33) 0.474 (0.311–0.723) 0.546 (0.355–0.84)
 High magnesium 4.36 (68) 3.4 (53) 0.772 (0.535–1.113) 0.95 (0.647–1.393)
 Low potassium with replacement 14.12 (220) 7.51 (117) 0.494 (0.39–0.625) 0.551 (0.429–0.706)
 High potassium 9.44 (147) 6.87 (107) 0.708 (0.546–0.918) 0.813 (0.621–1.066)
 Low sodium 39.41 (614) 30.62 (477) 0.678 (0.585–0.787) 0.707 (0.608–0.822)
 High sodium 7 (109) 6.03 (94) 0.854 (0.642–1.135) 1.004 (0.746–1.351)
 Low calcium with replacement 1.28 (20) 0.96 (15) 0.748 (0.381–1.466) 1.052 (0.517–2.14)
Metabolic acidosis
 Lactic (pH and lactate) 0.71 (11) 0.26 (4) 0.362 (0.115–1.139) 0.528 (0.161–1.728)
 Metabolic (pH and bicarbonate) 2.76 (43) 1.22 (19) 0.435 (0.252–0.75) 0.617 (0.342–1.115)
 Hyperchloremic (pH and chloride) 3.47 (54) 1.22 (19) 0.344 (0.203–0.583) 0.449 (0.256–0.786)
  1. aExcluded patients receiving warfarin