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Table 3 Lung mechanics

From: THAM reduces CO2-associated increase in pulmonary vascular resistance – an experimental study in lung-injured piglets

Parameter

Group

Baseline

Lung lavage

End

FRC (ml)

NT

386 (45)

224 (81)

278 (46)

1T

435 (105)

231 (54)

287 (116)

3T

341 (53)

158 (21)

202 (46)

Cexp (ml/cmH2O)

NT

47 (10)

37 (9)

47 (5)

1T

51 (19)

39 (17)

49 (17)

3T

51 (7)

41 (2)

50 (3)

  1. Abbreviations: Cexp compliance of the respiratory system obtained as the maximal slope of a full expiratory pressure-volume curve, FRC functional residual capacity, NT control animals that did not receive Tris(hydroxymethyl)aminomethane (THAM), 1T group that received THAM infusion for 1 h, 3T group that received THAM infusion for 3 h
  2. Lung lavage values obtained 30 minutes after lung lavage; end values obtained at the end of the experiment
  3. Values are mean (standard deviation)