Table 1 Arterial acid–base values, arterial and venous oxygenation, oxygen consumption, and venous admixture

pH

NT

7.40 (0.04)

7.40 (0.01)

7.14 (0.03)

7.11 (0.05)

7.12 (0.06)

1T

7.40 (0.05)

7.41 (0.02)

7.34 (0.05)^a

7.18 (0.05)^a

7.16 (0.07)

3T

7.43 (0.02)

7.40 (0.01)

7.35 (0.02)^a

7.39 (0.01)^a,b

7.16 (0.03)

PaCO₂ (kPa)

NT

6.6 (1.2)

6.0 (0.5)

12.3 (1.2)

13.5 (1.4)

13.8 (1.5)

1T

6.0 (0.6)

5.8 (0.3)

10.2 (0.9)^a

14.6 (2.4)

15.2 (3.3)

3T

6.3 (0.7)

5.9 (0.7)

10.6 (0.7)^a

13.1 (0.5)

22.6 (1.7)^a,b

PaO₂ (kPa)

NT

62.6 (12.7)

63.7 (7.4)

48.1 (12.0)

45.2 (12.3)

46.4 (11.8)

1T

65.2 (4.8)

65.0 (8.6)

59.8 (6.3)

49.4 (9.0)

53.3 (5.0)

3T

55.5 (15.5)

56.0 (4.6)

49.7 (4.1)

32.6 (7.6)§

30.0 (7.7)^a,b

Base excess (mEq/ml)

NT

4.8 (2.2)

2.7 (2.3)

1.3 (2.2)

1.8 (2.8)

3.4 (3.2)

1T

3.0 (3.2)

2.4 (1.5)

13.8 (3.5)^a

10.9 (3.1)^a

10.2 (2.1)^a

3T

6.2 (2.1)

2.4 (3.0)

16.0 (0.6)^a

31.2 (2.2)^a,b

27.8 (3.1)^a,b

HCO₃⁻ (mmol/L)

NT

28.5 (1.8)

27.2 (2.5)

29.7 (2.2)

30.8 (2.5)

32.3 (2.8)

1T

27.0 (2.8)

26.7 (1.5)

40.1 (3.2)^a

39.3 (3.2)^a

38.8 (2.5)^a

3T

29.8 (1.9)

26.8 (3.1)

42.3 (0.9)^a

58.6 (2.2)^a,b

57.2 (2.8)^a,b

SaO₂ (%)

NT

98 (0.3)

98 (0.2)

97 (0.4)

97 (0.6)

97 (0.6)

1T

98 (0.2)

98 (0.3)

98 (0.3)^a

98 (0.2)

97 (0.2)

3T

98 (0.8)

98 (0.1)^c

98 (0.2)^a

98 (0.3)

97 (0.8)

SvO₂ (%)

NT

71 (11)

53 (11)

63 (6.1)

67 (5.8)

67 (11)

1T

68 (4.6)

43 (5.2)

54 (10)

65 (6.5)

66 (10)

3T

70 (7.6)

47 (11)^c

61 (7.9)

69 (4.6)

74 (2.1)

VO₂ (ml/min)

NT

133 (32)

124 (22)

118 (23)

120 (9)

121 (21)

1T

128 (28)

142 (18)

131 (20)

139 (14)^c

140 (26)

3T

133 (30)^c

123 (18)^c

117 (7)

127 (7)

134 (13)

Q_s/Q_t (fraction)

NT

0.15 (0.03)

0.11 (0.04)

0.17 (0.04)

0.20 (0.07)

0.20 (0.08)

1T

0.13 (0.03)

0.09 (0.02)

0.11 (0.03)^a

0.17 (0.05)^c

0.15 (0.04)

3T

0.16 (0.02)^c

0.12 (0.02)^c

0.15 (0.03)^b

0.24 (0.04)

0.26 (0.06)^b

Lactate (mmol/L)

NT

1.1 (0.26)

1.3 (0.23)

0.7 (0.08)

0.6 (0.14)

0.6 (0.14)

1T

1.6 (0.81)

1.4 (0.14)

1.1 (0.19)^a

0.6 (0.14)

0.7 (0.19)

3T

1.1 (0.32)

1.2 (0.15)

0.9 (0.31)

0.9 (0.23)^a

1.3 (0.59)^a,b

ΔPaCO₂ (kPa)

NT

1.5 (0.6)

2.2 (0.6)

1.9 (0.5)

2.2 (0.7)

2.1 (0.8)

1T

1.8 (0.4)

2.6 (0.3)

0.7 (1.1)^a

2.1 (0.3)

2.2 (0.6)

3T

1.5 (0.3)

2.7 (0.3)

0.6 (0.4)^a

0.2 (0.6)^a,b

1.0 (0.7)^a,b