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Table 2 Correlation between ICU mortality and rifampin treatment in critically ill patients admitted with bacterial meningitis

From: Rifampin use in acute community-acquired meningitis in intensive care units: the French retrospective cohort ACAM-ICU study

Rifampin use

Non-survivors

Survivors

p Value

Entire population

n=23

n=134

 

 Rifampin during hospitalization

2/23

8.7 %

30/134

22.4 %

NS

 Rifampin during first 48 h of hospitalization

1/23

4.3 %

23/134

17.2 %

NS

 Rifampin during first 24 h of hospitalization

0/23

0.0 %

19/134

14.2 %

0.078

Streptococcus pneumoniae meningitis

n=18

n=58

 

 Rifampin during hospitalization

2/18

11.1 %

18/58

31.0 %

NS

 Rifampin during first 48 h of hospitalization

1/18

5.6 %

15/58

25.9 %

0.097

 Rifampin during first 24 h of hospitalization

0/18

0.0 %

13/58

22.4 %

0.031

  1. NS not significant
  2. Data are proportions of patients. They were compared with Fisher’s exact test
  3. p Values <0.1 are detailed. p Values <0.05 were considered significant (bold)