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Table 2 Correlation between ICU mortality and rifampin treatment in critically ill patients admitted with bacterial meningitis

From: Rifampin use in acute community-acquired meningitis in intensive care units: the French retrospective cohort ACAM-ICU study

Rifampin use Non-survivors Survivors p Value
Entire population n=23 n=134  
 Rifampin during hospitalization 2/23 8.7 % 30/134 22.4 % NS
 Rifampin during first 48 h of hospitalization 1/23 4.3 % 23/134 17.2 % NS
 Rifampin during first 24 h of hospitalization 0/23 0.0 % 19/134 14.2 % 0.078
Streptococcus pneumoniae meningitis n=18 n=58  
 Rifampin during hospitalization 2/18 11.1 % 18/58 31.0 % NS
 Rifampin during first 48 h of hospitalization 1/18 5.6 % 15/58 25.9 % 0.097
 Rifampin during first 24 h of hospitalization 0/18 0.0 % 13/58 22.4 % 0.031
  1. NS not significant
  2. Data are proportions of patients. They were compared with Fisher’s exact test
  3. p Values <0.1 are detailed. p Values <0.05 were considered significant (bold)