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Table 4 Multivariate analysis of risk factors for hospital mortality in patients with severe sepsis and septic shock

From: Adequate antibiotic therapy prior to ICU admission in patients with severe sepsis and septic shock reduces hospital mortality

 

Severe sepsis

Septic shock

 

Adjusted OR (95% CI)

p value

Adjusted OR (95% CI)

p value

Age

1.02 (1.00–1.05)

0.033

  

APACHE II score

1.07 (1.01–1.14)

0.020

1.11 (1.07–1.15)

<0.001

Cirrhosis

  

4.49 (1.55–13.04)

0.006

Immunosuppression

4.39 (1.64–11.72)

0.003

  

Urinary sepsis source

  

0.11 (0.05–0.27)

<0.001

Nosocomial infection

6.53 (2.74–15.55)

<0.001

  

Prior ICU adequate antimicrobial therapy

0.29 (0.13–0.63)

0.002

0.40 (0.24–0.65)

<0.001

  1. APACHE Acute Physiology and Chronic Health Evaluation, CI confidence interval, OR odds ratio