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Fig. 1 | Critical Care

Fig. 1

From: Common variants of NFE2L2 gene predisposes to acute respiratory distress syndrome in patients with severe sepsis

Fig. 1

Regional plot of association results. Upper panel: The y-axis represents the − log10-transformed p values for association tests. The x-axis represents the approximate location of the 40 single-nucleotide polymorphisms (SNPs) tested for association relative to the gene. Red circles depict associated SNPs after multiple comparison adjustments. Lower panel: This linkage disequilibrium (LD) plot is based on pairwise r 2 values among SNPs from the European population of the 1000 Genomes Project. Each diamond of the LD plot represents an r 2 value between two SNPs, schematically symbolized by a color gradient ranging from black (r 2 = 1, corresponding to complete LD) to gray (1 < r 2 < 0, moderate LD) and white (r 2 = 0, absence of LD)

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