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Table 1 Physiological parameters in minipigs after ICH

From: Hyperbaric oxygen therapy ameliorates acute brain injury after porcine intracerebral hemorrhage at high altitude

  Hours post-ICH PS (n = 6) PI (n = 10) HS (n = 6) HI (n = 10) HI-HBO (n = 10)
MAP (mmHg) 3 91.3 ± 2.5 93.8 ± 2.1 93.1 ± 2.6 94.2 ± 2.3 94.8 ± 2.2
6 91.4 ± 2.4 94.1 ± 2.0 92.2 ± 2.6 92.8 ± 2.2 94.9 ± 2.2
12 92.0 ± 2.5 93.0 ± 1.9 91.3 ± 2.4 93.7 ± 2.2 93.4 ± 2.0
Plasma glucose (mM) 3 4.45 ± 0.17 4.55 ± 0.13 4.48 ± 0.16 4.41 ± 0.12 4.49 ± 0.12
6 4.55 ± 0.17 4.48 ± 0.13 4.46 ± 0.15 4.53 ± 0.12 4.48 ± 0.12
12 4.35 ± 0.15 4.27 ± 0.12 4.36 ± 0.14 4.21 ± 0.11 4.38 ± 0.12
Core temperature (°C) 3 38.64 ± 0.06 38.73 ± 0.06 38.58 ± 0.07 38.70 ± 0.06 38.55 ± 0.08
6 38.58 ± 0.06 38.66 ± 0.06 38.53 ± 0.06 38.61 ± 0.06 38.48 ± 0.07
12 38.57 ± 0.05 38.60 ± 0.06 38.55 ± 0.06 38.53 ± 0.05 38.46 ± 0.06
pH 3 7.37 ± 0.02 7.37 ± 0.02 7.46 ± 0.03 a,b 7.47 ± 0.02 a,b 7.46 ± 0.02 a,b
6 7.38 ± 0.02 7.38 ± 0.01 7.46 ± 0.03 a,b 7.45 ± 0.02 a,b 7.48 ± 0.01 a,b
12 7.38 ± 0.02 7.39 ± 0.01 7.47 ± 0.03 a,b 7.46 ± 0.02 a,b 7.47 ± 0.02 a,b
HCO3 (mM) 3 24.50 ± 1.31 21.82 ± 1.09 18.18 ± 0.87 a,b 18.53 ± 0.65 a,b 18.46 ± 0.66 a,b
6 24.92 ± 1.27 22.03 ± 1.19 18.46 ± 0.84 a,b 17.31 ± 0.76 a,b 18.85 ± 0.62 a,b
12 23.87 ± 1.32 22.57 ± 1.17 17.97 ± 0.91 a,b 17.73 ± 0.67 a,b 18.64 ± 0.71 a,b
SaO2 3 97.1 ± 0.5 96.4 ± 0.4 86.7 ± 0.9 a,b 86.4 ± 0.6 a,b 87.0 ± 0.7 a,b
6 97.8 ± 0.6 96.7 ± 0.5 87.3 ± 0.8 a,b 85.9 ± 0.7 a,b 86.8 ± 0.7 a,b
12 97.5 ± 0.6 97.1 ± 0.5 87.2 ± 0.8 a,b 86.5 ± 0.6 a,b 86.7 ± 0.6 a,b
PaO2 (mmHg) 3 89.7 ± 1.5 84.5 ± 1.2 67.3 ± 1.4 a,b 63.1 ± 0.9 a,b 64.3 ± 1.0 a,b
6 90.7 ± 1.8 85.6 ± 1.1 68.3 ± 1.5 a,b 63.6 ± 1.0 a,b 63.9 ± 1.0 a,b
12 88.8 ± 1.5 88.4 ± 1.2 68.8 ± 1.5 a,b 65.3 ± 1.0 a,b 66.3 ± 1.2 a,b
PaCO2 (mmHg) 3 35.1 ± 1.0 32.9 ± 0.6 25.1 ± 0.6 a,b 23.5 ± 0.5 a,b 24.8 ± 0.5 a,b
6 34.5 ± 0.9 33.8 ± 0.6 24.9 ± 0.6 a,b 24.4 ± 0.6 a,b 25.6 ± 0.6 a,b
12 33.9 ± 0.8 34.2 ± 0.7 25.4 ± 0.7 a,b 24.1 ± 0.6 a,b 25.1 ± 0.6 a,b
  1. At each time point examined, plasma glucose, MAP and core temperature showed no significant differences between the five groups. Values of blood gas analysis showed significant differences between the plain (low altitude) and high-altitude animals. There was no significant difference between the plain groups, and between the high-altitude groups. HI: high altitude blood infusion group, HI-HBO: high-altitude blood infusion plus HBO therapy group, HS: high altitude sham operation group, MAP: mean arterial blood pressure, PI: plain blood infusion group, PS: plain sham operation group
  2. a P <0.05, compared with PS; b P <0.05, compared with PI