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Table 2 Characteristics of intubation procedures

From: Incidence of and risk factors for severe cardiovascular collapse after endotracheal intubation in the ICU: a multicenter observational study

  Total No collapse Collapse p-value
  (n = 885) (n = 621) (n = 264)
First intubation, n (%) 543 (61.4) 364 (58.6) 179 (67.8) 0.01
Anesthesiologist, n (%) 580 (65.5) 415 (66.8) 165 (62.5) 0.22
Fluid challenge, n (%) 336 (38.0) 229 (36.9) 107 (40.5) 0.33
SpO2 before ETI, mean ± SD 87.72 ± 0.5 88.4 ± 0.6 86.13 ± 0.8 0.03
NIV (out of preoxygenation), n (%) 324 (36.6) 185 (29.8) 139 (52.7) <0.0001
Drug for induction, n (%) 863 (97.5) 605 (97.4) 258 (97.7) 0.79
 Nesdonal, n (%) 25 (2.8) 17 (2.7) 8 (3.0) 0.81
 Propofol, n (%) 139 (15.7) 111 (17.9) 28 (10.6) 0.01
 Dose mg/kg, mean ± SD 2.13 ± 1.23 2.10 ± 1.23 2.27 ± 1.27 0.54
 Etomidate, n (%) 421 (47.6) 286 (46.1) 135 (51.1) 0.17
 Dose mg/kg, mean ± SD 0.45 ± .44 0.47 ± 0.46 0.42 ± 0.41 0.37
 Ketamine, n (%) 188 (21.2) 124 (20.0) 64 (24.2) 0.16
 Dose mg/kg, mean ± SD 2.77 ± 1.06 2.82 ± 1.10 2.66 ± 0.98 0.31
 Other, n (%) 39 (4.4) 24 (3.9) 15 (5.7) 0.23
Opioids, n (%) 74 (8.4) 53 (8.5) 21 (8.0) 0.78
 Fentanyl, n (%) 8 (0.9) 5 (0.8) 3 (1.1) 0.63
 Sufentanil, n (%) 53 (6.0) 42 (6.8) 11 (4.2) 0.14
 Remifentanil, n (%) 9 (1.0) 6 (1.0) 3 (1.1) 0.82
 Other, n (%) 3 (0.3) 3 (0.48) 0 (0) 0.26
NMBA, n (%) 770 (87.0) 543 (87.4) 227 (86.0) 0.56
 Suxamethonium, n (%) 646 (73.0) 446 (71.8) 200 (75.8) 0.23
 Rocuronium, n (%) 92 (10.4) 69 (11.1) 23 (8.7) 0.29
 Other, n (%) 45 (5.1) 32 (5.2) 13 (4.9) 0.89
MACOCHA score, n (%)     0.37
 <3 544 (83.9) 385 (84.8) 159 (82.0)  
 ≥3 104 (16.1) 69 (15.2) 35 (18.0)  
Preoxygenation, n (%) 841 (95.0) 585 (94.2) 256 (97.0) 0.08
Duration of preoxygenation, mean ± SD 1.23 (0.7) 1.21 (0.7) 1.29 (0.7) 0.11
NIV for preoxygenation, n (%) 371 (41.9) 233 (37.5) 138 (52.3) < 0.0001
Incident during ETI, n (%)     
 Inhalation, n (%) 102 (11.5) 66 (10.6) 36 (13.6) 0.20
 Cardiac rhythm abnormalities, n (%) 15 (1.7) 8 (1.3) 7 (2.7) 0.15
 Desaturation, n (%) 177 (20.0) 101 (16.3) 76 (28.8) < 0.0001
Implementation of sedation, n (%) 802 (90.6) 554 (89.2) 248 (93.9) 0.03
FIO2, mean ± SD 68.52 ± 0.9 65.57 ± 1.1 75.11 ± 1.5 < 0.0001
Tidal volume, mean ± SD 458.5 ± 2.9 459.01 ± 3.4 457.35 ± 5.1 0.79
PEEP, mean ± SD 5.76 ± 0.1 5.65 ± 0.1 6.01 ± 0.1 0.02
RM, n (%) 108 (12.2) 68 (11.0) 40 (15.2) 0.08
  1. FiO2 inspired oxygen concentration, MACOCHA score a seven-item (Mallampati score III or IV, obstructive sleep apnea syndrome, reduced mobility of cervical spine, limited mouth opening, coma, severe hypoxia, nonanesthesiologist as operator) simplified score, NMBA neuromuscular blocking agents, PEEP positive end-expiratory pressure, RM recruitment maneuver, SD standard deviation, SpO2 oxygen saturation, NIV noninvasive ventilation