The potential utility of urinary biomarkers for risk prediction in combat casualties: a prospective observational cohort study

Table 3 Sensitivity, specificity, negative predictive value and positive predictive value at optimal test characteristics

Marker	Optimal discriminant value*	Sensitivity	Specificity	Positive predictive value	Negative predictive value
CyC	2.24 ng/mg	0.67	0.84	40 %	94 %
IL-18	2.21 pg/mg	0.67	0.79	33 %	94 %
KIM-1	31.1 pg/mg	0.75	0.14	12 %	78 %
LFABP	1.76 ng/mg	0.50	0.83	32 %	91 %
NGAL	1.51 ng/mg	0.67	0.91	53 %	95 %
ISS	27	0.75	0.65	25 %	94 %

*Units are expressed in ng/mg creatinine or pg/mg creatinine. CyC cystatin C, IL-18 interleukin-18, KIM-1 kidney injury molecule-1, L-FABP liver-type fatty acid-binding protein, NGAL neutrophil gelatinase-associated lipocalin, ISS injury severity score

ISSN: 1364-8535