TY - JOUR AU - Corrêa, Thiago Domingos AU - Jakob, Stephan Matthias AU - Takala, Jukka PY - 2015 DA - 2015/12/01 TI - Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? JO - Critical Care SP - 264 VL - 19 IS - 1 AB - Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient’s baseline condition, and present directions for future research in this field. SN - 1364-8535 UR - https://doi.org/10.1186/s13054-015-0958-x DO - 10.1186/s13054-015-0958-x ID - Corrêa2015 ER -