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Table 4 Medications which are known potential triggers of mast cell degranulation

From: Critical care management of systemic mastocytosis: when every wasp is a killer bee

 

Opioids

Hypnotics

Muscle relaxants

(Local) anaesthesia

Volatile anaesthetics

Avoid

  

Mivacurium

Nefopam

 

Atracurium

Avoid rapid perfusion

Morphine Codeine

Thiopental

Succinylcholine Rocuronium

Lidocain Bupivacain

 

(if possible, use alternative agents)

Low risk

Fentanyl Sufentanil Remifentanil Alfentanil

Midazolam Propofol Etomidate Ketamine

Cis-atracurium Pancuronium Vecuronium

Ropivacain

Desfurane Sevoflurane Enflurane Isoflurane

Paracetamol