|
Parameter
|
Beta coefficient
|
Standard error
|
Odds ratio (95 % CI)
|
p value
|
|---|
|
Univariate logistic regression
|
|
Age
|
0.013
|
0.012
|
1.014 (0.989, 1.038)
|
0.272
|
|
Male gender
|
−0.491
|
0.423
|
0.612 (0.267, 1.402)
|
0.246
|
|
Immunocompromised
|
0.575
|
0.460
|
1.778 (0.721, 4.381)
|
0.211
|
|
SOFA score, diagnosis day
|
0.130
|
0.071
|
1.139 (0.991, 1.307)
|
0.066
|
|
PaO2/FiO2, diagnosis day
|
0.003
|
0.003
|
1.003 (0.996, 1.010)
|
0.423
|
|
SOFA score, biopsy day
|
0.326
|
0.085
|
1.385 (1.173, 1.635)
|
<0.001*
|
|
PaO2/FiO2, biopsy day
|
−0.007
|
0.003
|
0.993 (0.987, 0.999)
|
0.03*
|
|
Treatment changes after biopsy
|
−0.770
|
0.415
|
0.463 (0.205, 1.044)
|
0.063
|
|
DAD on biopsy
|
1.123
|
0.423
|
3.075 (1.343, 7.039)
|
0.008*
|
|
Multivariate logistic regression
|
|
DAD on biopsy
|
1.268
|
0.481
|
3.554 (1.385, 9.120)
|
0.008*
|
|
SOFA score, biopsy day
|
0.353
|
0.093
|
1.424 (1.187, 1.707)
|
<0.001*
|
|
Constant
|
−2.522
|
0.698
|
0.080
|
<0.001*
|
- *p <0.05. In multivariate logistic regression, the Hosmer-Lemeshow test results (χ2 = 3.371, degrees of freedom = 8, p = 0.909). Abbreviations: SOFA Sequential organ failure assessment, PaO2 Arterial partial pressure of oxygen, FiO2 fraction of inspired oxygen, DAD diffuse alveolar damage
