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Table 4 Univariate and multivariate logistic regression analysis of clinical variables associated with hospital mortality

From: Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy

Parameter Beta coefficient Standard error Odds ratio (95 % CI) p value
Univariate logistic regression
  Age 0.013 0.012 1.014 (0.989, 1.038) 0.272
  Male gender −0.491 0.423 0.612 (0.267, 1.402) 0.246
  Immunocompromised 0.575 0.460 1.778 (0.721, 4.381) 0.211
  SOFA score, diagnosis day 0.130 0.071 1.139 (0.991, 1.307) 0.066
  PaO2/FiO2, diagnosis day 0.003 0.003 1.003 (0.996, 1.010) 0.423
  SOFA score, biopsy day 0.326 0.085 1.385 (1.173, 1.635) <0.001*
  PaO2/FiO2, biopsy day −0.007 0.003 0.993 (0.987, 0.999) 0.03*
  Treatment changes after biopsy −0.770 0.415 0.463 (0.205, 1.044) 0.063
  DAD on biopsy 1.123 0.423 3.075 (1.343, 7.039) 0.008*
Multivariate logistic regression
  DAD on biopsy 1.268 0.481 3.554 (1.385, 9.120) 0.008*
  SOFA score, biopsy day 0.353 0.093 1.424 (1.187, 1.707) <0.001*
  Constant −2.522 0.698 0.080 <0.001*
  1. *p <0.05. In multivariate logistic regression, the Hosmer-Lemeshow test results (χ2 = 3.371, degrees of freedom = 8, p = 0.909). Abbreviations: SOFA Sequential organ failure assessment, PaO2 Arterial partial pressure of oxygen, FiO2 fraction of inspired oxygen, DAD diffuse alveolar damage