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Table 3 Demographic and clinical characteristics of survivors versus. non-survivors in patients with ARDS who had open lung biopsy

From: Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy

Characteristics Survivors (n=40) Non-survivors (n=61) P value
Age 54.5 ± 15.4 58.3 ± 17.6 0.274
Gender (male/female) 23/17 42/19 0.244
Immunocompromised (%) 32.5 21.3 0.208
APACHE II score, diagnosis day 23.4 ± 5.3 23.1 ± 5.7 0.838
SOFA score, diagnosis day 5.4 ± 2.6 6.6 ± 3.5 0.06
PaO2/FiO2 (mm Hg), diagnosis day 136.5 ± 55.3 146.3 ± 63.4 0.427
SOFA score, biopsy day 5.2 ± 2.7 8.1 ± 3.4 <0.001*
PaO2/FiO2 (mm Hg), biopsy day 167.6 ± 69.3 136.3 ± 64.6 0.023*
PEEP (cm H2O), biopsy day 11.2 ± 2.7 12.2 ± 2.7 0.071
Tidal volume (mL), biopsy day 437.1 ± 86.0 413.4 ± 107.2 0.372
Duration from diagnosis to biopsy (days) 7.1 ± 6.4 8.1 ± 7.1 0.232
Operative complication rate (%) 5 18 0.056
DAD on biopsy (%) 40 67.2 0.007*
Treatment changes after biopsy (%) 60 41 0.061
  1. All values are expressed as number of patients (%) or mean ± SD; *p values <0.05. Abbreviations: ARDS Acute respiratory distress syndrome, APACHE Acute physiology and chronic health evaluation; SOFA Sequential organ failure assessment, PaO2 Arterial partial pressure of oxygen, FiO2 Fraction of inspired oxygen, PEEP Positive end-expiratory pressure, DAD Diffuse alveolar damage