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Fig. 4 | Critical Care

Fig. 4

From: Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction

Fig. 4

Matrix ChIP analysis of changes in histone H3 lysine acetylation (H3KAc) levels at Angpt1, Tek, Kdr, and Ngal genes in experimental acute lung injury-induced sepsis (ALI-sepsis). Sheared cross-linked lungs, kidneys, and livers were assayed by using an antibody to acetylated histone H3 lysine 9 and 14, H3KAc. ChIP analysis was done as in Fig. 3. Data represent mean ± standard error of the mean (n = 12 animals from each group), expressed as a fraction of input. Statistical differences between two means (P value) are shown as in Fig. 2. ChIP, chromatin immunoprecipitation platform

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Critical Care

ISSN: 1364-8535